Evidence map›Paper›PMID 37514190›Full record

ReviewPharmaceutics2023

Hacking the Immune Response to Solid Tumors: Harnessing the Anti-Cancer Capacities of Oncolytic Bacteria.

Jason M Roe, Kevin Seely, Caleb J Bussard, Emily Eischen Martin, Elizabeth G Mouw, Kenneth W Bayles, Michael A Hollingsworth, Amanda E Brooks, Kaitlin M Dailey

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
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  7. Review
  8. Article
  9. Impact on Human Health ofInternational journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jason M RoeCollege of Osteopathic Medicine, Rocky Vista University, Ivins, UT 84738, USA.
Kevin SeelyCollege of Osteopathic Medicine, Rocky Vista University, Ivins, UT 84738, USA.ORCID 0000-0003-0390-813X
Caleb J BussardCollege of Osteopathic Medicine, Rocky Vista University, Parker, CO 80130, USA.
Emily Eischen MartinCollege of Osteopathic Medicine, Rocky Vista University, Ivins, UT 84738, USA.ORCID 0000-0003-2598-3114
Elizabeth G MouwCollege of Osteopathic Medicine, Rocky Vista University, Ivins, UT 84738, USA.ORCID 0009-0007-3154-6718
Kenneth W BaylesDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Michael A HollingsworthEppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Amanda E BrooksCollege of Osteopathic Medicine, Rocky Vista University, Ivins, UT 84738, USA.ORCID 0000-0001-9785-5969
Kaitlin M DaileyEppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0001-8834-0293
Rocky Vista University · USUniversity of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncolytic bacteria are a classification of bacteria with a natural ability to specifically target solid tumors and, in the process, stimulate a potent immune response. Currently, these include species of

Indexed as

bacterial-mediated cancer therapeuticsengineered bacterial therapeuticshost–pathogen interactionimmune responsemicrobiomeoncologyoncolytic bacteriaprogrammable medicinesolid tumorsynthetic biologytumor therapy

Identifiers

PMID37514190
PMCPMC10384176
OpenAlexW4385226547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.