Evidence map›Paper›PMID 37514163›Full record

ReviewPharmaceutics2023

Recent Advances in Polycaprolactones for Anticancer Drug Delivery.

Abhi Bhadran, Tejas Shah, Godwin K Babanyinah, Himanshu Polara, Somayeh Taslimy, Michael C Biewer, Mihaela C Stefan

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abhi BhadranDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0000-0001-5162-8664
Tejas ShahDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.
Godwin K BabanyinahDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.
Himanshu PolaraDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.
Somayeh TaslimyDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.
Michael C BiewerDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.
Mihaela C StefanDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0000-0003-2475-4635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(ε-Caprolactone)s are biodegradable and biocompatible polyesters that have gained considerable attention for drug delivery applications due to their slow degradation and ease of functionalization. One of the significant advantages of polycaprolactone is its ability to attach various functionalities to its backbone, which is commonly accomplished through ring-opening polymerization (ROP) of functionalized caprolactone monomer. In this review, we aim to summarize some of the most recent advances in polycaprolactones and their potential application in drug delivery. We will discuss different types of polycaprolactone-based drug delivery systems and their behavior in response to different stimuli, their ability to target specific locations, morphology, as well as their drug loading and release capabilities.

Indexed as

catalystdrug delivery systemsfunctional caprolactone monomerspolycaprolactonespolymeric micellesring opening polymerizationstimuli-responsive polymerstargeting

Identifiers

PMID37514163
PMCPMC10385458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.