Evidence map›Paper›PMID 37514022›Full record

ArticlePharmaceutics2023

Therapeutic Drug Monitoring of Anti-TNFα Inhibitors: A Matter of Cut-Off Ranges.

Stefania Cheli, Diego Savino, Francesca Penagini, Gianvincenzo Zuccotti, Giovanna Zuin, Emilio Clementi, Dario Cattaneo

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stefania CheliUnit of Clinical Pharmacology, ASST Fatebenefratelli Sacco, University Hospital, 20157 Milano, Italy.ORCID 0000-0002-2837-5248
Diego SavinoUnit of Clinical Pharmacology, ASST Fatebenefratelli Sacco, University Hospital, 20157 Milano, Italy.
Francesca PenaginiPediatric Department, "Vittore Buzzi" Children's Hospital, University of Milan, 20154 Milan, Italy.
Gianvincenzo ZuccottiPediatric Department, "Vittore Buzzi" Children's Hospital, University of Milan, 20154 Milan, Italy.ORCID 0000-0002-2795-9874
Giovanna ZuinPediatrics, IRCCS San Gerardo dei Tintori Foundation, 20900 Monza, Italy.
Emilio ClementiScientific Institute IRCCS Eugenio Medea, 23842 Bosisio Parini, Italy.
Dario CattaneoUnit of Clinical Pharmacology, ASST Fatebenefratelli Sacco, University Hospital, 20157 Milano, Italy.ORCID 0000-0003-1512-6530
ASST Fatebenefratelli Sacco · ITUniversity of Milan · ITAzienda Ospedaliera San Gerardo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic drug monitoring (TDM) is a useful tool for optimising the use of anti-TNFα inhibitors in patients with inflammatory bowel diseases (IBDs). Recently, point-of-care methods for the quantification of drug levels and anti-drug antibodies (ADAs) have been developed to overcome the limitations of conventional enzyme-linked immunoabsorbent assays (ELISAs). Here, we evaluated the performance, interchangeability, and agreement between an automated ELISA-based immunoassay (CHORUS Promonitor) and the lateral flow assay (RIDA

Indexed as

adalimumabadalimumab antibodiesanti-infliximab antibodiesinflammatory bowel diseaseinfliximabtherapeutic drug monitoring

Identifiers

PMID37514022
PMCPMC10386140
OpenAlexW4382585197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.