Evidence map›Paper›PMID 37513993›Full record

ArticlePharmaceutics2023

Cholinium-Based Ionic Liquids as Promising Antimicrobial Agents in Pharmaceutical Applications: Surface Activity, Antibacterial Activity and Ecotoxicological Profile.

María Teresa García, Elena Bautista, Ana de la Fuente, Lourdes Pérez

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

María Teresa GarcíaDepartment of Surfactants and Nanobiotechnology, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.ORCID 0000-0001-9967-3472
Elena BautistaDepartment of Surfactants and Nanobiotechnology, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.
Ana de la FuenteDepartment of Surfactants and Nanobiotechnology, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.
Lourdes PérezDepartment of Surfactants and Nanobiotechnology, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.ORCID 0000-0002-3696-021X

Funding

Spanish Ministry of Science and Innovation, Spanish Research Agency (AEI) and FEDER/UE CTQ2017-88948-P; PTA2018-015441-I; AGAUR 2021-SGR-00507
6 · The paper itself

Abstract

Cholinium-based ionic liquids are compounds increasingly studied in pharmaceutics and biomedicine to enhance bioavailability in drug delivery systems and as bioactive ingredients in pharmaceutical formulations. However, their potential as antimicrobial agents has scarcely been investigated. Herein, we explored the antimicrobial activity of a series of surface-active cholinium-based ionic liquids (Chol-ILs). For this purpose, Chol-ILs with alkyl chains of 10-16 carbon atoms were synthesized and their self-assembly in aqueous medium was investigated. Subsequently, their antimicrobial activity against a panel of clinically relevant bacteria and their ability to eradicate MRSA and

Indexed as

antimicrobial activitybiodegradationbiofilm eradicationbiofilm inhibitioncholinium-based ionic liquidsecotoxicityhemolysissurface activity

Identifiers

PMID37513993
PMCPMC10385515

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.