Evidence map›Paper›PMID 37513938›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents-A Novel Polymer Formulation for Anticancer Therapy.

Yvonne Lerchbammer-Kreith, Michaela Hejl, Nadine S Sommerfeld, Xian Weng-Jiang, Uchechukwu Odunze, Ryan D Mellor, David G Workman, Michael A Jakupec, Andreas G Schätzlein, Ijeoma F Uchegbu and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Clustered, SERS-Active, Ultrasmall AuNPs for Photothermal Therapy.International journal of nanomedicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Yvonne Lerchbammer-KreithInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.
Michaela HejlInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.
Nadine S SommerfeldInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.
Xian Weng-JiangSchool of Pharmacy, University College London, Brunswick Square 29-39, London WC1N 1AX, UK.
Uchechukwu OdunzeSchool of Pharmacy, University College London, Brunswick Square 29-39, London WC1N 1AX, UK.ORCID 0000-0001-9552-3290
Ryan D MellorSchool of Pharmacy, University College London, Brunswick Square 29-39, London WC1N 1AX, UK.ORCID 0000-0002-0677-5603
David G WorkmanSchool of Pharmacy, University College London, Brunswick Square 29-39, London WC1N 1AX, UK.
Michael A JakupecInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.ORCID 0000-0001-7945-1426
Andreas G SchätzleinSchool of Pharmacy, University College London, Brunswick Square 29-39, London WC1N 1AX, UK.ORCID 0000-0003-3907-6603
Ijeoma F UchegbuSchool of Pharmacy, University College London, Brunswick Square 29-39, London WC1N 1AX, UK.ORCID 0000-0001-9586-6867
Mathea S GalanskiInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.ORCID 0000-0001-7965-7379
Bernhard K KepplerInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.
University College London · GBUniversity of Vienna · AT

Funding

Hochschuljubiläumsfonds of the City of Vienna H-320163/2018
6 · The paper itself

Abstract

Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents. Consequently, we synthesised cytotoxic platinum(IV) conjugates of cisplatin, carboplatin and oxaliplatin by coupling via amide bonds to five GCPQ polymers differing in their degree of palmitoylation and quaternisation. The conjugates were characterised by

Indexed as

anticancerdrug deliveryplatinum(IV) complexesquaternary ammonium glycol chitosan (GCPQ)

Identifiers

PMID37513938
PMCPMC10386324
OpenAlexW4384785047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.