ArticlePathogens (Basel, Switzerland)2023
Novel Metallo-β-Lactamase
Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Transcriptional analysis of quorum sensing genes cviI/cviR and violacein synthesis genes in imipenem non-susceptible Chromobacterium violaceum.Molecular biology reports · 2025Article
- Mutations inMicrobiology spectrum · 2025Article
- A Case of Severe Septicemia WithClinical case reports · 2025Article
- Severe SystemicTropical medicine and infectious disease · 2024Article
- Strategies to Name Metallo-β-Lactamases and Number Their Amino Acid Residues.Antibiotics (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveWe aimed to describe a colistin (COL)-resistant (R)
methodsIn 2019, a 12 year old child was injured with a thorn in a lagoon. The child was hospitalized due to sepsis and multiple abscesses. Cvi was isolated from skin and soft tissue and tracheal aspirate. The patient was successfully treated with imipenem (IMI) plus amikacin. Antimicrobial susceptibility was assessed by disk diffusion, broth microdilution, and the E-test. Carbapenemase activity was assayed by double-disk synergy and microbiological tests. Resistance, virulence, and additional gene searches were performed by in silico analysis of sequences obtained by whole-genome sequencing (WGS). A maximum likelihood phylogenetic tree was built with public Cvi genomes.
resultsR was seen for IMI and COL. Expression of a metallo-β-lactamase was confirmed. Genome analysis revealed
conclusionsThis is the second report of infection by Cvi in Argentina. This pathogen carried a new gene,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.