Evidence map›Paper›PMID 37513721›Full record

ReviewPathogens (Basel, Switzerland)2023

Probiotics and Postbiotics as an Alternative to Antibiotics: An Emphasis on Pigs.

Md Sekendar Ali, Eon-Bee Lee, Walter H Hsu, Kyoungho Suk, Syed Al Jawad Sayem, H M Arif Ullah, Seung-Jin Lee, Seung-Chun Park

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 61 citations in OpenAlex.

  1. Role of C17 fengycin B fromApplied and environmental microbiology · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Synbiotic Diet PreventsCurrent issues in molecular biology · 2026
    Article
  8. Article
  9. Review
  10. Review
  11. Impact of Farm Management Practices onFoods (Basel, Switzerland) · 2026
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Animals : an open access journal from MDPI · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Md Sekendar AliDepartment of Biomedical Science and Department of Pharmacology, School of Medicine, Brain Science and Engineering Institute, Kyungpook National University, Daegu 41944, Republic of Korea.
Eon-Bee LeeLaboratory of Veterinary Pharmacokinetics and Pharmacodynamics, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0002-8668-4508
Walter H HsuDepartment of Biomedical Sciences, Iowa State University, Ames, IA 50014, USA.
Kyoungho SukDepartment of Biomedical Science and Department of Pharmacology, School of Medicine, Brain Science and Engineering Institute, Kyungpook National University, Daegu 41944, Republic of Korea.ORCID 0000-0002-9555-4203
Syed Al Jawad SayemLaboratory of Veterinary Pharmacokinetics and Pharmacodynamics, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0001-5580-8443
H M Arif UllahDepartment of Neurobiology, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0001-6874-3095
Seung-Jin LeeDevelopment and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.
Seung-Chun ParkLaboratory of Veterinary Pharmacokinetics and Pharmacodynamics, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0001-8539-1087
Kyungpook National University · KRInternational Islamic University Chittagong · BDIowa State University · USKorea Institute of Toxicology · KRUniversity of Utah · US

Funding

Animal and Plant Quarantine Agency Z-1543081-2020-22-02
6 · The paper itself

Abstract

Probiotics are being used as feed/food supplements as an alternative to antibiotics. It has been demonstrated that probiotics provide several health benefits, including preventing diarrhea, irritable bowel syndrome, and immunomodulation. Alongside probiotic bacteria-fermented foods, the different structural components, such as lipoteichoic acids, teichoic acids, peptidoglycans, and surface-layer proteins, offer several advantages. Probiotics can produce different antimicrobial components, enzymes, peptides, vitamins, and exopolysaccharides. Besides live probiotics, there has been growing interest in consuming inactivated probiotics in farm animals, including pigs. Several reports have shown that live and killed probiotics can boost immunity, modulate intestinal microbiota, improve feed efficiency and growth performance, and decrease the incidence of diarrhea, positioning them as an interesting strategy as a potential feed supplement for pigs. Therefore, effective selection and approach to the use of probiotics might provide essential features of using probiotics as an important functional feed for pigs. This review aimed to systematically investigate the potential effects of lactic acid bacteria in their live and inactivated forms on pigs.

Indexed as

antibioticspigletspigspostbioticsprobiotics

Identifiers

PMID37513721
PMCPMC10383198
OpenAlexW4382458859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.