Evidence map›Paper›PMID 37513594›Full record

ArticleNutrients2023

Gestational Weight Gain Relates to DNA Methylation in Umbilical Cord, Which, In Turn, Associates with Offspring Obesity-Related Parameters.

Berta Mas-Parés, Sílvia Xargay-Torrent, Ariadna Gómez-Vilarrubla, Gemma Carreras-Badosa, Anna Prats-Puig, Francis De Zegher, Lourdes Ibáñez, Judit Bassols, Abel López-Bermejo

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Berta Mas-ParésPediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, 17190 Salt, Spain.
Sílvia Xargay-TorrentPediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, 17190 Salt, Spain.
Ariadna Gómez-VilarrublaMaterno-Fetal Metabolic Research Group, (Girona Biomedical Research Institute) IDIBGI, 17190 Salt, Spain.ORCID 0000-0001-8183-5218
Gemma Carreras-BadosaPediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, 17190 Salt, Spain.
Anna Prats-PuigUniversity School of Health and Sport (EUSES), University of Girona, 17190 Salt, Spain.ORCID 0000-0002-5253-3808
Francis De ZegherDepartment of Development & Regeneration, University of Leuven, 3000 Leuven, Belgium.
Lourdes IbáñezEndocrinology Department, Research Institute Sant Joan de Déu, University of Barcelona, 08950 Esplugues, Spain.
Judit BassolsMaterno-Fetal Metabolic Research Group, (Girona Biomedical Research Institute) IDIBGI, 17190 Salt, Spain.ORCID 0000-0001-8821-6655
Abel López-BermejoPediatric Endocrinology Research Group, (Girona Biomedical Research Institute) IDIBGI, 17190 Salt, Spain.
Institut d'Investigació Biomèdica de Girona · ESUniversitat de Girona · ESInstituto de Salud Carlos III · ESKU Leuven · BE

Funding

Instituto de Salud Carlos III PI19/00451Instituto de Salud Carlos III PI20/00399Instituto de Salud Carlos III PI22_00366
6 · The paper itself

Abstract

Excessive gestational weight gain (GWG) has a negative impact on offspring's health. Epigenetic modifications mediate these associations by causing changes in gene expression. We studied the association between GWG and DNA methylation in umbilical cord tissue; and determined whether the DNA methylation and the expression of corresponding annotated genes were associated with obesity-related parameters in offspring at 6 years of age. The methylated CpG sites (CpGs) associated with GWG were identified in umbilical cord tissue by genome-wide DNA methylation (

Indexed as

Gestational Weight GainPediatric ObesityBody Mass IndexDNA MethylationHumansUmbilical CordWeight GainDNA methylationgestational weight gainobesity

Identifiers

PMID37513594
PMCPMC10386148
OpenAlexW4384666091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.