Evidence map›Paper›PMID 37513518›Full record

ArticleNutrients2023

LRG1 Associates with Iron Deficiency Anemia Markers in Adolescents.

Rashed Alhammad, Mohamed Abu-Farha, Abdur Rahman, Thangavel Alphonse Thanaraj, Lemia Shaban, Reem Alsabah, Samar Hamad, Maha M Hammad, Arshad Channanath, Fahd Al-Mulla and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rashed AlhammadDepartment of Pharmacology, Faculty of Medicine, Kuwait University, Kuwait City 13110, Kuwait.
Mohamed Abu-FarhaBiochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.ORCID 0000-0001-8357-1252
Abdur RahmanDepartment of Food Science and Nutrition, College of Life Sciences, Kuwait University, Kuwait City 13110, Kuwait.ORCID 0000-0002-5115-3053
Thangavel Alphonse ThanarajDepartment of Community Medicine and Behavioural Sciences, Faculty of Medicine, Kuwait University, Kuwait City 13110, Kuwait.ORCID 0000-0002-4574-5343
Lemia ShabanDepartment of Food Science and Nutrition, College of Life Sciences, Kuwait University, Kuwait City 13110, Kuwait.
Reem AlsabahDepartment of Community Medicine and Behavioural Sciences, Faculty of Medicine, Kuwait University, Kuwait City 13110, Kuwait.
Samar HamadBiochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Maha M HammadBiochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.ORCID 0000-0002-8974-8255
Arshad ChannanathGenetics and Bioinformatics Department, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.
Fahd Al-MullaGenetics and Bioinformatics Department, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.ORCID 0000-0001-5409-3829
Jehad AbubakerBiochemistry and Molecular Biology Department, Dasman Diabetes Institute, Kuwait City 15462, Kuwait.ORCID 0000-0003-0681-7305
Dasman Diabetes Institute · KWKuwait University · KW

Funding

Dasman Diabetes Institute RA HM2017-026Kuwait University WF02/13
6 · The paper itself

Abstract

Leucine-rich α-2 glycoprotein1 (LRG1) has been shown to be associated with several health conditions; however, its association with iron deficiency anemia, especially in children, has not been previously explored. In this study, we investigated the association between LRG1 and several iron deficiency anemia markers, including hemoglobin (Hb), albumin, red cell distribution width (RDW), iron, ferritin, and Hb transferrin saturation. A total of 431 participants were included in this analysis aged between 11 and 14 years. Higher LRG1 levels were observed in children diagnosed with anemia [31.1 (24.6, 43.2) µg/mL] compared to non-anemic children [29.2 (22.7-35.95) µg/mL]. Statistically significant differences of LRG1 level across the three groups (tertiles) of Hb, iron, transferrin saturation, albumin, RDW, ferritin, and WBC were observed. Strong negative correlations were observed between LRG1 and Hb (Spearman's rho = -0.11,

Indexed as

Anemia, Iron-DeficiencyAdolescentAlbuminsBiomarkersChildFerritinsGlycoproteinsHemoglobinsHumansIronLeucineTransferrinAlbuminsBiomarkersFerritinsGlycoproteinsHemoglobinsIronLeucineLRG1 protein, humanTransferrinferritinHbHIF-1αiron deficiency anemiaLRG

Identifiers

PMID37513518
PMCPMC10384480
OpenAlexW4384038228

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.