Evidence map›Paper›PMID 37513358›Full record

ArticleMolecules (Basel, Switzerland)2023

Finding a Novel Chalcone-Cinnamic Acid Chimeric Compound with Antiproliferative Activity against MCF-7 Cell Line Using a Free-Wilson Type Approach.

Isis A Y Ventura-Salazar, Francisco J Palacios-Can, Leticia González-Maya, Jessica Nayelli Sánchez-Carranza, Mayra Antunez-Mojica, Rodrigo Said Razo-Hernández, Laura Alvarez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isis A Y Ventura-SalazarCentro de Investigaciones Químicas, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca 62210, Mexico.ORCID 0000-0003-1242-9384
Francisco J Palacios-CanCentro de Investigación en Dinámica Celular, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca 62210, Mexico.ORCID 0000-0002-8162-5269
Leticia González-MayaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca 62210, Mexico.ORCID 0000-0002-4456-1235
Jessica Nayelli Sánchez-CarranzaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca 62210, Mexico.ORCID 0000-0002-6555-6267
Mayra Antunez-MojicaCONAHCYT-Instituto de Investigación en Ciencias Básicas y Aplicadas, Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca 62210, Mexico.ORCID 0000-0002-1075-5947
Rodrigo Said Razo-HernándezCentro de Investigación en Dinámica Celular, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca 62210, Mexico.ORCID 0000-0002-9716-9376
Laura AlvarezCentro de Investigaciones Químicas, Instituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca 62210, Mexico.ORCID 0000-0001-7464-9898

Funding

Consejo Nacional de Ciencia y Tecnología 240801Consejo Nacional de Ciencia y Tecnología LN321131
6 · The paper itself

Abstract

In this work, we carried out the design and synthesis of new chimeric compounds from the natural cytotoxic chalcone 2',4'-dihydroxychalcone (2',4'-DHC,

Indexed as

Antineoplastic AgentsChalconeChalconesCell Line, TumorCell ProliferationCinnamatesDrug Screening Assays, AntitumorHumansMCF-7 CellsMolecular StructurePyridinesStructure-Activity RelationshipAntineoplastic AgentsChalconeChalconesCinnamatescinnamic acidPyridineschalconecytotoxic activityhybrid moleculeQSAR

Identifiers

PMID37513358
PMCPMC10383513

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.