Evidence map›Paper›PMID 37513351›Full record

ArticleMolecules (Basel, Switzerland)2023

Synthesis, Biological, Spectroscopic and Computational Investigations of Novel

Jakub Mikus, Piotr Świątek, Patrycja Przybyła, Edward Krzyżak, Aleksandra Marciniak, Aleksadra Kotynia, Aleksandra Redzicka, Benita Wiatrak, Paulina Jawień, Tomasz Gębarowski and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Novel Isoxazole-Based Antifungal Drug Candidates.International journal of molecular sciences · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jakub MikusStudent Science Club of Medicinal Chemistry, Department of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.
Piotr ŚwiątekDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0003-4613-025X
Patrycja PrzybyłaStudent Science Club of Medicinal Chemistry, Department of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.
Edward KrzyżakDepartment of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0002-5000-2448
Aleksandra MarciniakDepartment of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0003-2225-7897
Aleksadra KotyniaDepartment of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0003-0730-8975
Aleksandra RedzickaDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0003-1508-8327
Benita WiatrakDepartment of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.ORCID 0000-0002-1404-2274
Paulina JawieńDepartment of Biostructure and Animal Physiology, Division of Animal Anatomy, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Kożuchowska 1, 51-631 Wrocław, Poland.ORCID 0000-0001-8512-8174
Tomasz GębarowskiDepartment of Biostructure and Animal Physiology, Division of Animal Anatomy, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Kożuchowska 1, 51-631 Wrocław, Poland.ORCID 0000-0002-8742-0790
Łukasz SzczukowskiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0002-9768-6269
Wroclaw Medical University · PLWrocław University of Environmental and Life Sciences · PL

Funding

Wroclaw Medical University SUBZ.D070.23.026Wroclaw Medical University SUBZ.D290.23.031
6 · The paper itself

Abstract

Secure and efficient treatment of diverse pain and inflammatory disorders is continually challenging. Although NSAIDs and other painkillers are well-known and commonly available, they are sometimes insufficient and can cause dangerous adverse effects. As yet reported, derivatives of pyrrolo[3,4-

Indexed as

Cyclooxygenase InhibitorsHydrazonesLipoxygenase InhibitorsPyridazinesPyrrolesCell LineCell Membrane PermeabilityComputer SimulationFibroblastsHumansCyclooxygenase InhibitorsHydrazonesLipoxygenase InhibitorsPyridazinesPyrrolespyrrolo(3,4-d)pyridazinoneAAGADMEcyclooxygenasefluorescence spectroscopyHSAinflammationlipoxygenasemolecular dockingNAHpyridazinone

Identifiers

PMID37513351
PMCPMC10383271
OpenAlexW4384826554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.