Evidence map›Paper›PMID 37513326›Full record

ArticleMolecules (Basel, Switzerland)2023

Computational Investigation of Conformational Properties of Short Azapeptides: Insights from DFT Study and NBO Analysis.

Mouna El Khabchi, Mohammed Mcharfi, Mohammed Benzakour, Asmae Fitri, Adil Touimi Benjelloun, Jong-Won Song, Kang-Bong Lee, Ho-Jin Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mouna El KhabchiLIMAS, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdallah University, Fez 30000, Morocco.
Mohammed McharfiLIMAS, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdallah University, Fez 30000, Morocco.
Mohammed BenzakourLIMAS, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdallah University, Fez 30000, Morocco.
Asmae FitriLIMAS, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdallah University, Fez 30000, Morocco.
Adil Touimi BenjellounLIMAS, Department of Chemistry, Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdallah University, Fez 30000, Morocco.ORCID 0000-0002-5297-9113
Jong-Won SongDepartment of Chemistry Education, Daegu University, Daegudae-ro 201, Gyeongsan-si 38453, Republic of Korea.ORCID 0000-0003-3387-3265
Kang-Bong LeeClimate and Environmental Research Institute, Korea Institute of Science & Technology, Hwarang-ro 14-gil 5, Seoul 02792, Republic of Korea.
Ho-Jin LeeDepartment of Natural Sciences, Southwest Tennessee Community College, Memphis, TN 38134, USA.ORCID 0000-0002-3251-4984

Funding

Korea Ministry of Science and ICT 2020R1A2C1102741
6 · The paper itself

Abstract

Azapeptides have gained much attention due to their ability to enhance the stability and bioavailability of peptide drugs. Their structural preferences, essential to understanding their function and potential application in the peptide drug design, remain largely unknown. In this work, we systematically investigated the conformational preferences of three azaamino acid residues in tripeptide models, Ac-azaXaa-Pro-NHMe [Xaa = Asn (

Indexed as

AmidesPeptidesProtein ConformationWaterAmidesPeptidesWaterAsx turnazapeptidescis-trans amide bondconformational preferencesdensity functional theoryhydrogen bondsβ-turn

Identifiers

PMID37513326
PMCPMC10386235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.