Evidence map›Paper›PMID 37513298›Full record

ArticleMolecules (Basel, Switzerland)2023

Insights into the Effect of Chitosan and β-Cyclodextrin Hybridization of Zeolite-A on Its Physicochemical and Cytotoxic Properties as a Bio-Carrier for 5-Fluorouracil: Equilibrium and Release Kinetics Studies.

Mashael D Alqahtani, May N Bin Jumah, Saleha A AlZahrani, Ahmed A Allam, Mostafa R Abukhadra, Stefano Bellucci

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Mashael D AlqahtaniDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0003-0043-0847
May N Bin JumahDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0002-3017-9924
Saleha A AlZahraniDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Ahmed A AllamZoology Department, Faculty of Science, Beni-Suef University, Beni-Suef 65211, Egypt.
Mostafa R AbukhadraGeology Department, Faculty of Science, Beni-Suef University, Beni-Suef 65211, Egypt.ORCID 0000-0001-5404-7996
Stefano BellucciINFN-Laboratori Nazionali di Frascati, Via E. Fermi 54, 00044 Frascati, Italy.ORCID 0000-0003-0326-6368
Princess Nourah bint Abdulrahman University · SABeni-Suef University · EGIstituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic zeolite-A (ZA) was hybridized with two different biopolymers (chitosan and β-cyclodextrin) producing biocompatible chitosan/zeolite-A (CS/ZA) and β-cyclodextrin/zeolite-A (CD/ZA) biocomposites. The synthetic composites were assessed as bio-carriers of the 5-fluorouracil drug (5-Fu) with enhanced properties, highlighting the impact of the polymer type. The hybridization by the two biopolymers resulted in notable increases in the 5-Fu loading capacities, to 218.2 mg/g (CS/ZA) and 291.3 mg/g (CD/ZA), as compared to ZA (134.2 mg/g). The loading behaviors using ZA as well as CS/ZA and CD/ZA were illustrated based on the classic kinetics properties of pseudo-first-order kinetics (R

Indexed as

Antineoplastic Agentsbeta-CyclodextrinsChitosanZeolitesDrug CarriersFluorouracilKineticsAntineoplastic Agentsbeta-CyclodextrinsChitosanDrug CarriersFluorouracilZeolites5-fluorouracilbiopolymerscompositescytotoxicityloadingzeolite-A

Identifiers

PMID37513298
PMCPMC10384421
OpenAlexW4384526126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.