Evidence map›Paper›PMID 37513287›Full record

ReviewMolecules (Basel, Switzerland)2023

Structural Modification and Biological Activity of Polysaccharides.

Ting Zhao, Min Yang, Lina Ma, Xinglong Liu, Qiteng Ding, Guodong Chai, Yang Lu, Hewei Wei, Shuai Zhang, Chuanbo Ding

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
26.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 130 citations in OpenAlex.

  1. Recent advances inFood chemistry: X · 2026
    Review
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  13. Frontiers in nutrition · 2026
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  19. Frontiers in nutrition · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ting ZhaoCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Min YangCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Lina MaCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Xinglong LiuCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Qiteng DingScientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
Guodong ChaiScientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
Yang LuScientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
Hewei WeiScientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
Shuai ZhangScientific and Technological Innovation Center of Health Products and Medical Materials with Characteristic Resources of Jilin Province, Jilin Agricultural University, Changchun 130118, China.
Chuanbo DingCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Jilin Agricultural University · CNJilin Agricultural Science and Technology University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural polysaccharides are macromolecular substances with a wide range of biological activities. The structural modification of polysaccharides by chemical means can enhance their biological activity. This paper reviews the latest research reports on the chemical modification of natural polysaccharides. At present, the modification methods of polysaccharides mainly include sulfation, phosphorylation, carboxymethylation, socialization, methylation and acetylation. The chemical and physical structures of the modified polysaccharides were detected via ultraviolet spectroscopy, FT-IR, high-performance liquid chromatography, ultraviolet spectroscopy, gas chromatography-mass spectrometry, nuclear magnetic resonance and scanning electron microscopy. Modern pharmacological studies have shown that the modified polysaccharide has various biological activities, such as antioxidant, antitumor, immune regulation, antiviral, antibacterial and anticoagulant functions in vitro. This review provides fresh ideas for the research and application of polysaccharide structure modification.

Indexed as

AntioxidantsPolysaccharidesMagnetic Resonance SpectroscopyPhosphorylationSpectroscopy, Fourier Transform InfraredAntioxidantsPolysaccharidesbiological activitypolysaccharidestructural characterizationstructural modification

Identifiers

PMID37513287
PMCPMC10384959
OpenAlexW4384557489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.