Solid-Phase Synthesis of 2-Benzothiazolyl and 2-(Aminophenyl)benzothiazolyl Amino Acids and Peptides.

Spyridon Mourtas, Vasileios Athanasopoulos, Dimitrios Gatos, Kleomenis Barlos

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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1 citing paper in PubMed.

Investigation for the easy and efficient synthesis of 1RSC advances · 2025
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5 · Who and what money

Authors and funding

4 authors.

Spyridon MourtasDepartment of Chemistry, University of Patras, 26510 Rio Patras, Greece.ORCID 0000-0003-1204-1574

Vasileios AthanasopoulosDepartment of Chemistry, University of Patras, 26510 Rio Patras, Greece.

Dimitrios GatosDepartment of Chemistry, University of Patras, 26510 Rio Patras, Greece.

Kleomenis BarlosCBL-Patras, Patras Industrial Area, Block 1, 25018 Patras, Greece.

Funding

University of Patras 81762

6 · The paper itself

Abstract

2-benzothiazoles and 2-(aminophenyl)benzothiazoles represent biologically interesting heterocycles with high pharmacological activity. The combination of these heterocycles with amino acids and peptides is of special interest, as such structures combine the advantages of amino acids and peptides with the advantages of the 2-benzothiazolyl and 2-(aminophenyl)benzothiazolyl pharmacophore group. In this work, we developed an easy and efficient method for the solid-phase synthesis of 2-benzothiazolyl (BTH) and 2-(aminophenyl)benzothiazolyl (AP-BTH) C-terminal modified amino acids and peptides with high chiral purity.

Indexed as

Amino AcidsSolid-Phase Synthesis TechniquesAminesBenzothiazolesPeptidesAminesAmino AcidsBenzothiazolesPeptides2-(aminophenyl)benzothiazoles2-benzothiazolesamino acidschiral purityracemizationsolid-phase synthesis

Identifiers

PMID37513284

DOI10.3390/molecules28145412

PMCPMC10385376

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