Evidence map›Paper›PMID 37513270›Full record

ArticleMolecules (Basel, Switzerland)2023

Coptisine Inhibits Influenza Virus Replication by Upregulating p21.

Ming-Feng He, Jian-Hui Liang, Yan-Ni Shen, Chao-Wei Zhang, Kuang-Yang Yang, Li-Chu Liu, Qian Xie, Chun Hu, Xun Song, Yan Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Plants (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Current topics in medicinal chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Ming-Feng HeFoshan Hospital of Traditional Chinese Medicine, Foshan 528000, China.
Jian-Hui LiangCenter for Translation Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Yan-Ni ShenCenter for Translation Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Chao-Wei ZhangSchool of Pharmaceutical Science, Shenzhen University, Shenzhen 518000, China.
Kuang-Yang YangFoshan Hospital of Traditional Chinese Medicine, Foshan 528000, China.
Li-Chu LiuFoshan Hospital of Traditional Chinese Medicine, Foshan 528000, China.
Qian XieCenter for Translation Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Chun HuKey Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.ORCID 0000-0003-2919-2870
Xun SongCollege of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China.ORCID 0000-0002-2566-3519
Yan WangCenter for Translation Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.ORCID 0000-0003-0671-7312
Chinese Academy of Sciences · CNFoshan Hospital of TCM · CNShenyang Pharmaceutical University · CNShenzhen Technology University · CNShenzhen University · CN

Funding

Guangdong Basic and Applied Basic Research Fund 2020A1515011342Project for High Efficiency and Developed Hospital at Foshan City 202200087 to M.F.H.; 202000189, 202200089 to K.Y.Y.Shenzhen Science and Technology Innovation Fund JCYJ20190807160601672
6 · The paper itself

Abstract

The activation of innate antiviral immunity is a promising approach for combatting viral infections. In this study, we screened Chinese herbs that activated human immunity and identified coptisine as a potent inhibitor of the influenza virus with an EC

Indexed as

BerberineInfluenza, HumanAntiviral AgentsHumansProtein Serine-Threonine KinasesVirus ReplicationAntiviral AgentsBerberinecoptisineMELK protein, humanProtein Serine-Threonine Kinasesantiviralcoptisineinfluenza virusp21

Identifiers

PMID37513270
PMCPMC10386263
OpenAlexW4384298384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.