Evidence map›Paper›PMID 37513079›Full record

ArticleNanomaterials (Basel, Switzerland)2023

Probing Polarity and pH Sensitivity of Carbon Dots in

Gilad Yahav, Shweta Pawar, Anat Lipovsky, Akanksha Gupta, Aharon Gedanken, Hamootal Duadi, Dror Fixler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gilad YahavInstitute of Nanotechnology and Advanced Materials, Faculty of Engineering, Bar-Ilan University, Ramat Gan 52900, Israel.ORCID 0009-0002-4824-4752
Shweta PawarInstitute of Nanotechnology and Advanced Materials, Faculty of Engineering, Bar-Ilan University, Ramat Gan 52900, Israel.
Anat LipovskyInstitute of Nanotechnology and Advanced Materials, Faculty of Engineering, Bar-Ilan University, Ramat Gan 52900, Israel.
Akanksha GuptaInstitute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel.
Aharon GedankenInstitute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel.ORCID 0000-0002-1243-2957
Hamootal DuadiInstitute of Nanotechnology and Advanced Materials, Faculty of Engineering, Bar-Ilan University, Ramat Gan 52900, Israel.
Dror FixlerInstitute of Nanotechnology and Advanced Materials, Faculty of Engineering, Bar-Ilan University, Ramat Gan 52900, Israel.ORCID 0000-0003-0963-7908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular monitoring of pH and polarity is crucial for understanding cellular processes and functions. This study employed pH- and polarity-sensitive nanomaterials such as carbon dots (CDs) for the intracellular sensing of pH, polarity, and viscosity using integrated time-resolved fluorescence anisotropy (FA) imaging (TR-FAIM) and fluorescence lifetime (FLT) imaging microscopy (FLIM), thereby enabling comprehensive characterization. The functional groups on the surface of CDs exhibit sensitivity to changes in the microenvironment, leading to variations in fluorescence intensity (FI) and FLT according to pH and polarity. The FLT of CDs in aqueous solution changed gradually from 6.38 ± 0.05 ns to 8.03 ± 0.21 ns within a pH range of 2-8. Interestingly, a complex relationship of FI and FLT was observed during measurements of CDs with decreasing polarity. However, the FA and rotational correlation time (

Indexed as

carbon dots (CDs)E. colifluorescence lifetime imaging microscopy (FLIM)frequency domain (FD)intracellular sensingpH sensorpolarity sensortime-resolved fluorescence anisotropy imaging (TR-FAIM)

Identifiers

PMID37513079
PMCPMC10384995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.