Evidence map›Paper›PMID 37512537›Full record

ArticleMetabolites2023

The Effects of a High Concentration of Dissolved Oxygen on Actinobacteria from Lake Baikal.

Maria E Dmitrieva, Ekaterina V Malygina, Alexander Y Belyshenko, Victoria N Shelkovnikova, Natalia A Imidoeva, Maria M Morgunova, Tamara Y Telnova, Anfisa A Vlasova, Denis V Axenov-Gribanov

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maria E DmitrievaLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0002-9229-1954
Ekaterina V MalyginaLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0002-2673-0226
Alexander Y BelyshenkoLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0002-8812-2250
Victoria N ShelkovnikovaLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0002-4411-7521
Natalia A ImidoevaLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0002-6327-5517
Maria M MorgunovaLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0002-7939-1432
Tamara Y TelnovaLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0003-2606-3766
Anfisa A VlasovaLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0002-7817-5156
Denis V Axenov-GribanovLaboratory of Experimental Neurophysiology, Department for Research and Development, Irkutsk State University, 1 Karl Marx Str., 664003 Irkutsk, Russia.ORCID 0000-0003-2020-6084
Irkutsk State University · RU

Funding

Ministry of Education and Science of Russian Federation FZZE 2021-0013
6 · The paper itself

Abstract

Among the diversity of microorganisms, the rarest and least explored are microorganisms that live in conditions of high oxygen in the environment and can experience the effects of natural oxidative stress. Here we suggest that the actinobacteria of Lake Baikal, sampled in the littoral zone, may produce natural products with antioxidant activity. The current study aimed to assess the effects of experimentally increased amounts of oxygen and ozone on the morphology of actinobacteria, DNA mutations, and antioxidant potential. In this experiment, we cultivated actinobacteria in liquid culture under conditions of natural aeration and increased concentrations of dissolved oxygen and ozone. Over a period of three months, bacterial samples were collected every week for further analysis. Morphological changes were assessed using the Gram method. A search for DNA mutations was conducted for the highly conserved 16S rRNA gene. The evaluation of antioxidant activity was performed using the DPPH test. The biotechnological potential was evaluated using high-resolution liquid chromatography-mass spectrometry approaches supplemented with the dereplication of natural products. We demonstrated the synthesis of at least five natural products by the

Indexed as

actinobacteriaantioxidantsDNA mutationsLake Baikaloxidative stressoxygenoxyphilic bacteriaROSsecondary metabolites

Identifiers

PMID37512537
PMCPMC10386110
OpenAlexW4383724387

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.