Evidence map›Paper›PMID 37512526›Full record

ArticleMetabolites2023

Fecal Microbiota and Associated Volatile Organic Compounds Distinguishing No-Adenoma from High-Risk Colon Adenoma Adults.

Kyriaki Katsaounou, Danae Yiannakou, Elpiniki Nikolaou, Cameron Brown, Paris Vogazianos, Aristos Aristodimou, Jianxiang Chi, Paul Costeas, Agapios Agapiou, Elisavet Frangou and 5 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Kyriaki KatsaounouDepartment of Biological Sciences, University of Cyprus, Nicosia 2109, Cyprus.
Danae YiannakouStremble Ventures Ltd., Limassol 4042, Cyprus.ORCID 0009-0008-8200-4668
Elpiniki NikolaouAVVA Pharmaceuticals Ltd., Limassol 4001, Cyprus.
Cameron BrownStremble Ventures Ltd., Limassol 4042, Cyprus.
Paris VogazianosStremble Ventures Ltd., Limassol 4042, Cyprus.ORCID 0000-0001-9991-6059
Aristos AristodimouStremble Ventures Ltd., Limassol 4042, Cyprus.
Jianxiang ChiKaraiskakio Foundation, Nicosia 2032, Cyprus.
Paul CosteasKaraiskakio Foundation, Nicosia 2032, Cyprus.
Agapios AgapiouDepartment of Chemistry, University of Cyprus, Nicosia 2109, Cyprus.ORCID 0000-0001-8371-0910
Elisavet FrangouNicosia General Hospital, Nicosia 2029, Cyprus.
George TsiaoussisNicosia General Hospital, Nicosia 2029, Cyprus.
George PotamitisNikis Center, Nicosia 1082, Cyprus.
Athos AntoniadesStremble Ventures Ltd., Limassol 4042, Cyprus.ORCID 0000-0002-5789-5103
Christos ShammasAVVA Pharmaceuticals Ltd., Limassol 4001, Cyprus.
Yiorgos ApidianakisDepartment of Biological Sciences, University of Cyprus, Nicosia 2109, Cyprus.
University of Cyprus · CYLimassol General Hospital · CYNicosia General Hospital · CY

Funding

Research and Innovation Foundation EXCELLENCE/1216/0523
6 · The paper itself

Abstract

Microbiota and the metabolites they produce within the large intestine interact with the host epithelia under the influence of a range of host-derived metabolic, immune, and homeostatic factors. This complex host-microbe interaction affects intestinal tumorigenesis, but established microbial or metabolite profiles predicting colorectal cancer (CRC) risk are missing. Here, we aimed to identify fecal bacteria, volatile organic compounds (VOC), and their associations that distinguish healthy (non-adenoma, NA) from CRC prone (high-risk adenoma, HRA) individuals. Analyzing fecal samples obtained from 117 participants ≥15 days past routine colonoscopy, we highlight the higher abundance of Proteobacteria and

Indexed as

dysbacteriosismetabolitesnutrientspathobionts

Identifiers

PMID37512526
PMCPMC10383435
OpenAlexW4383262630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.