Evidence map›Paper›PMID 37512489›Full record

ArticleMetabolites2023

Pilot Study on the Use of Untargeted Metabolomic Fingerprinting of Liquid-Cytology Fluids as a Diagnostic Tool of Malignancy for Thyroid Nodules.

Grégoire D'Andréa, Lun Jing, Isabelle Peyrottes, Jean-Marie Guigonis, Fanny Graslin, Sabine Lindenthal, Julie Sanglier, Isabel Gimenez, Juliette Haudebourg, Clair Vandersteen and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Grégoire D'AndréaOtorhinolaryngology and Head and Neck Surgery Department, Institut Universitaire de la Face et du Cou, GCS Nice University Hospital-Antoine Lacassagne Center, Côte d'Azur University, 31 Avenue de Valombrose, 06103 Nice, France.ORCID 0000-0003-3838-513X
Lun JingLaboratory Transporter in Imaging and Radiotherapy in Oncology (TIRO), UMR E4320 TIRO-MATOs, Direction de la Recherche Fondamentale (DRF), Institut des Sciences du Vivant Fréderic Joliot, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Faculté de Médecine, Côte d'Azur University, 28 Avenue de Valombrose, CEDEX 2, 06107 Nice, France.ORCID 0000-0001-6397-0627
Isabelle PeyrottesDepartment of Cytopathology and Anatomopathology, Antoine Lacassagne Center, 33 Av. de Valombrose, 06189 Nice, France.
Jean-Marie GuigonisLaboratory Transporter in Imaging and Radiotherapy in Oncology (TIRO), UMR E4320 TIRO-MATOs, Direction de la Recherche Fondamentale (DRF), Institut des Sciences du Vivant Fréderic Joliot, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Faculté de Médecine, Côte d'Azur University, 28 Avenue de Valombrose, CEDEX 2, 06107 Nice, France.
Fanny GraslinLaboratory Transporter in Imaging and Radiotherapy in Oncology (TIRO), UMR E4320 TIRO-MATOs, Direction de la Recherche Fondamentale (DRF), Institut des Sciences du Vivant Fréderic Joliot, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Faculté de Médecine, Côte d'Azur University, 28 Avenue de Valombrose, CEDEX 2, 06107 Nice, France.
Sabine LindenthalLaboratory Transporter in Imaging and Radiotherapy in Oncology (TIRO), UMR E4320 TIRO-MATOs, Direction de la Recherche Fondamentale (DRF), Institut des Sciences du Vivant Fréderic Joliot, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Faculté de Médecine, Côte d'Azur University, 28 Avenue de Valombrose, CEDEX 2, 06107 Nice, France.
Julie SanglierDepartment of Radiology, Antoine Lacassagne Center, 33 Av. de Valombrose, 06189 Nice, France.
Isabel GimenezDepartment of Cytopathology and Anatomopathology, Antoine Lacassagne Center, 33 Av. de Valombrose, 06189 Nice, France.
Juliette HaudebourgDepartment of Cytopathology and Anatomopathology, Antoine Lacassagne Center, 33 Av. de Valombrose, 06189 Nice, France.
Clair VandersteenOtorhinolaryngology and Head and Neck Surgery Department, Institut Universitaire de la Face et du Cou, GCS Nice University Hospital-Antoine Lacassagne Center, Côte d'Azur University, 31 Avenue de Valombrose, 06103 Nice, France.ORCID 0000-0001-5597-2040
Alexandre BozecOtorhinolaryngology and Head and Neck Surgery Department, Institut Universitaire de la Face et du Cou, GCS Nice University Hospital-Antoine Lacassagne Center, Côte d'Azur University, 31 Avenue de Valombrose, 06103 Nice, France.ORCID 0000-0002-8576-3052
Nicolas GuevaraOtorhinolaryngology and Head and Neck Surgery Department, Institut Universitaire de la Face et du Cou, GCS Nice University Hospital-Antoine Lacassagne Center, Côte d'Azur University, 31 Avenue de Valombrose, 06103 Nice, France.ORCID 0000-0002-4286-6465
Thierry PourcherLaboratory Transporter in Imaging and Radiotherapy in Oncology (TIRO), UMR E4320 TIRO-MATOs, Direction de la Recherche Fondamentale (DRF), Institut des Sciences du Vivant Fréderic Joliot, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Faculté de Médecine, Côte d'Azur University, 28 Avenue de Valombrose, CEDEX 2, 06107 Nice, France.ORCID 0000-0003-2839-4622
Commissariat à l'Énergie Atomique et aux Énergies Alternatives · FRCentre Antoine Lacassagne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although it is the gold standard for assessing the malignancy of thyroid nodules (TNs) preoperatively, the cytological analysis of fine-needle aspiration cytology (FNAC) samples results in 20-30% of cases in indeterminate lesions (ITNs). As two-thirds of these lesions will appear benign after diagnostic surgery, improved preoperative diagnostic methods need to be developed. In this pilot study, we evaluate if the metabolomic profiles of liquid-based (CytoRich

Indexed as

deep learningdiagnostic biomarkersfine-needle aspiration cytologyindeterminate thyroid nodulesmachine learningmetabolomicsthyroid cancer

Identifiers

PMID37512489
PMCPMC10384948
OpenAlexW4382024089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.