Evidence map›Paper›PMID 37511938›Full record

ArticleLife (Basel, Switzerland)2023

Two-Level Corpectomy and Fusion vs. Three-Level Anterior Cervical Discectomy and Fusion without Plating: Long-Term Clinical and Radiological Outcomes in a Multicentric Retrospective Analysis.

Giorgio Lofrese, Sokol Trungu, Alba Scerrati, Pasquale De Bonis, Francesco Cultrera, Lorenzo Mongardi, Nicola Montemurro, Amedeo Piazza, Massimo Miscusi, Luigino Tosatto and 2 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Reply to the Letter to the Editor of M. Zhang, et al. concerning "Surgical strategies and outcomes in degenerative myelopathy at the cervico-thoracic junction: a multicenter retrospective analysis" by Umana GE, et al. (Eur Spine J [2025]: doi:10.1007/s00586-025-09139-7).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giorgio LofreseNeurosurgery Unit, Bufalini Hospital, 47521 Cesena, Italy.ORCID 0000-0001-5874-7340
Sokol TrunguNESMOS Department, "Sapienza" University of Rome, Sant'Andrea Hospital, 00185 Rome, Italy.ORCID 0000-0002-5087-6006
Alba ScerratiDepartment of Neurosurgery, S. Anna University Hospital, 44124 Ferrara, Italy.ORCID 0000-0002-8607-5323
Pasquale De BonisDepartment of Neurosurgery, S. Anna University Hospital, 44124 Ferrara, Italy.ORCID 0000-0002-9879-8940
Francesco CultreraNeurosurgery Unit, Bufalini Hospital, 47521 Cesena, Italy.
Lorenzo MongardiDepartment of Neurosurgery, S. Anna University Hospital, 44124 Ferrara, Italy.
Nicola MontemurroDepartment of Neurosurgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-3686-8907
Amedeo PiazzaNESMOS Department, "Sapienza" University of Rome, Sant'Andrea Hospital, 00185 Rome, Italy.ORCID 0000-0001-5360-5810
Massimo MiscusiNESMOS Department, "Sapienza" University of Rome, Sant'Andrea Hospital, 00185 Rome, Italy.
Luigino TosattoNeurosurgery Unit, Bufalini Hospital, 47521 Cesena, Italy.
Antonino RacoNESMOS Department, "Sapienza" University of Rome, Sant'Andrea Hospital, 00185 Rome, Italy.
Luca RicciardiNESMOS Department, "Sapienza" University of Rome, Sant'Andrea Hospital, 00185 Rome, Italy.ORCID 0000-0001-5110-8386

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) represent effective alternatives in the management of multilevel cervical spondylotic myelopathy (CSM). A consensus on which of these techniques should be used is still missing.

methodsThe databases of three centers were reviewed (January 2011-December 2018) for patients with three-level CSM, who underwent three-level ACDF without plating or two-level ACCF with expandable cage (VBRC) or mesh (VBRM). Demographic data, surgical strategy, complications, and implant failure were analyzed. The Neck Disability Index (NDI), the Visual Analog Scale (VAS), and the cervical lordosis were compared between the two techniques at 3 and 12 months. Logistic regression analyses investigated independent factors influencing clinical and radiological outcomes.

resultsTwenty-one and twenty-two patients were included in the ACDF and ACCF groups, respectively. The median follow-up was 18 months. ACDFs were associated with better clinical outcomes at 12 months (NDI: 8.3% vs. 19.3%,

conclusionsThree-level ACDF without plating was associated with better clinical outcomes than two-level ACCF despite worse losses in lordosis correction, which is ideal for fragile patients without retrovertebral compressions. In multilevel CSM, the relationship between the degree of lordosis correction and clinical outcome advantages still needs to be investigated.

Indexed as

ACCFACDFanterior cervical corpectomy and fusionanterior cervical discectomy and fusioncervical spondylotic myelopathycorpectomydiscectomyfusion

Identifiers

PMID37511938
PMCPMC10381458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.