ReviewLife (Basel, Switzerland)2023
Periodontal Pathogens and Adverse Pregnancy Outcomes: A Narrative Review.
Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Evaluating Dickkopf-1 as a biomarker: insights into periodontitis, rheumatoid arthritis, and their comorbidity-a systematic review and meta-analysis.Frontiers in dental medicine · 2025Pooled it
- Traditional Foods, Oral Microbiome, and Systemic Health: Molecular Pathways Linking Nutrition and Oral Disease Prevention.International journal of molecular sciences · 2026Review
- Is There an Association Between Periodontitis and Gestational Diabetes? A Systematic Review and Meta-Analysis.Dentistry journal · 2026Review
- A scientometric analysis of research related to the 'oral-placental axis' hypothesis: current status, hotspots, and future directions.Frontiers in cellular and infection microbiology · 2026Review
- Oral prophylaxis for the reduction of interdental dysbiosis-associated red complex pathogens during pregnancy: a randomized clinical trial.Frontiers in medicine · 2026Article
- Mathematical Modeling of Obstetric Variables: Influence of COVID-19, Periodontal Disease and Dental Care During Pregnancy.Biomedicines · 2025Article
- Immune Markers Linking Chronic Periodontitis with Gestational Complications: A Systematic Review.Pakistan journal of medical sciences · 2025Article
- Periodontitis-associated Fusobacterium nucleatum promotes ulcerative colitis by ferroptosis-mediated gut barrier disruption.NPJ biofilms and microbiomes · 2025Article
- Oral health status and quality of life among pregnant women with oral health problems: a descriptive study.BMC oral health · 2025Article
- Oral microbiome dysbiosis in women with a history of pregnancy loss: a metagenomic cross-sectional study.Scientific reports · 2025Article
- Orthodontic treatment in patients with chronic periodontitis significantly improves periodontal health.American journal of translational research · 2025Article
- Impact of Hormones and Lifestyle on Oral Health During Pregnancy: A Prospective Observational Regression-Based Study.Medicina (Kaunas, Lithuania) · 2024Observational
- The Influence of Dental Status and Blood Parameters Characterizing Endogenous Intoxication on the Timing of Childbirth.Medicina (Kaunas, Lithuania) · 2024Article
- The Impact of Periodontal Disease on Preterm Birth and Preeclampsia.Journal of personalized medicine · 2024Review
- [Changes of parameters associated with anemia of inflammation in patients with stage Ⅲ periodontitis before and after periodontal initial therapy].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024Article
- Pregnancy-related dental problems: A review.Heliyon · 2024Review
- Inhibitory Effects of the Heat-Killed Lactic Acid BacteriumCurrent therapeutic research, clinical and experimental · 2024Article
- Impact of Non-Surgical Periodontal Treatment on the Concentration and Level of MRP-8/14 (Calprotectin) as an Inflammatory Biomarker in Women with Periodontitis and Rheumatoid Arthritis: A Quasi-Experimental Study.Diseases (Basel, Switzerland) · 2024Article
- Profiling oral health status, values, and related quality of life in patients with oral cancer: a pilot study.Frontiers in oral health · 2023Article
- Periodontal pathogens of the interdental microbiota in a 3 months pregnant population with an intact periodontium.Frontiers in microbiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontal disease is a multi-microbial infection of the teeth-supporting apparatus that manifests as clinical attachment loss and alveolar bone loss. The association between periodontal disease and systemic diseases has been proposed in the literature owing to the former's chronic state of inflammation, and adverse pregnancy outcomes are no exception. As a result of periodontal pathogen invasion, a series of systemic inflammatory and immunologic events affecting the safety of the fetoplacental unit may unfold. This may be further exaggerated by physiologic hormonal and metabolic fluctuations during pregnancy. This can not only negatively affect the gestation period and consequently cause preterm low weight but also complicate the pregnancy via preeclampsia and gestational diabetes. This narrative review article aims to provide a summary of relevant available evidence pertinent to the relationship between periodontal diseases, associated periodontal pathogens and virulence mechanisms mediated by pro-inflammatory cytokines and prostaglandins, and adverse pregnancy outcomes. Furthermore, this article highlights some of the literature addressing the impact of periodontal therapy interventions and pregnancy outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.