Evidence map›Paper›PMID 37511877›Full record

ArticleLife (Basel, Switzerland)2023

The Early Initiation Advantages of Physical Therapy in Multiple Sclerosis-A Pilot Study.

Florin Mihai Marcu, Ilarie Brihan, Anamaria Ciubara, Vasile Valeriu Lupu, Nicoleta Negrut, Anamaria Jurcau, Ancuta Lupu, Stefan Lucian Burlea, Felicia Dragan, Lacramioara Ionela Butnariu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Associations between lifestyle factors and 2.5-year clinical outcomes differ by time since multiple sclerosis diagnosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Florin Mihai MarcuFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.ORCID 0000-0002-9095-2595
Ilarie BrihanFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.
Anamaria CiubaraFaculty of Medicine and Pharmacy, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0000-0003-0740-3702
Vasile Valeriu LupuFaculty of General Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-2640-8795
Nicoleta NegrutFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.ORCID 0000-0002-0380-3381
Anamaria JurcauFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.ORCID 0000-0002-0793-2877
Ancuta LupuFaculty of General Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-8147-3632
Stefan Lucian BurleaPublic Health and Management Department, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Felicia DraganFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.
Lacramioara Ionela ButnariuFaculty of General Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-6713-4244
Alina Elena Ignat"Al. I. Cuza" University, 700506 Iasi, Romania.
Alexandru Bogdan CiubaraFaculty of Medicine and Pharmacy, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0000-0002-8037-6002
University of Oradea · ROGrigore T. Popa University of Medicine and Pharmacy · RO"Dunarea de Jos" University of Galati · ROAlexandru Ioan Cuza University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Multiple sclerosis (MS), a chronic progressive neurological disorder which affects the central nervous system (CNS), can result in disorders of all the functions controlled by the CNS: motor, sensory, cognitive and emotional. Physical therapy (PT), conducted through proprioceptive neuromuscular facilitation (PNF) techniques, can be customized to the individual patient's needs and has the potential to improve the patient's evolution. This study aims to establish if PT based on PNF techniques has a beneficial role in MS treatment. (2) Methods: We performed a prospective study on 40 patients who were diagnosed with MS and previously treated only with MS drug treatment (DT). These patients have participated in a PT program throughout one year. At the beginning and at the end of our study, after one year, we have assessed the following parameters: timed walk for 25 feet (Timed 25-Foot Walk test- T25FW test), dexterity of the upper limbs (9-Hole Peg Test-9HPT), disability level (Expanded Disability Status Scale-EDSS) and cognitive function (Paced Auditory Serial Addition Test-PASAT. (3) Results: In subjects in the early stages of MS, lower limb mobility improved significantly, T25FW decreasing from 6.46 to 5.80 (

Indexed as

central nervous systemmultiple sclerosisphysical therapyquality of life

Identifiers

PMID37511877
PMCPMC10381402
OpenAlexW4383068498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.