Evidence map›Paper›PMID 37511635›Full record

ArticleJournal of personalized medicine2023

Mortality Risk Prediction in Abdominal Septic Shock Treated with Polymyxin-B Hemoperfusion: A Retrospective Cohort Study.

Sergio Garcia-Ramos, Estrela Caamaño, Patrocinio Rodríguez Benítez, Pilar Benito, Alberto Calvo, Silvia Ramos, Mercedes Power, Ignacio Garutti, Patricia Piñeiro

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Endotoxic Septic Shock: Diagnosis and Treatment.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sergio Garcia-RamosDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.
Estrela CaamañoDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.ORCID 0000-0003-0836-5226
Patrocinio Rodríguez BenítezDepartment of Nephrology, Gregorio Marañon National Hospital, 28007 Madrid, Spain.
Pilar BenitoDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.
Alberto CalvoDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.
Silvia RamosDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.
Mercedes PowerDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.ORCID 0000-0003-3442-3135
Ignacio GaruttiDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.ORCID 0000-0001-8284-2903
Patricia PiñeiroDepartment of Anaesthesiology and Critical Care Medicine, Gregorio Marañon National Hospital, 28007 Madrid, Spain.ORCID 0000-0003-0223-2262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endotoxin, a component of the cell membrane of gram-negative bacteria, is a trigger for dysregulated inflammatory response in sepsis. Extracorporeal purification of endotoxin, through adsorption with polymyxin B, has been studied as a therapeutic option for sepsis. Previous studies suggest that it could be effective in patients with high endotoxin levels or patients with septic shock of moderate severity. Here, we perform a retrospective, single-centre cohort study of 93 patients suffering from abdominal septic shock treated with polymyxin-B hemoperfusion (PMX-HP) between 2015 and 2020. We compared deceased and surviving patients one month after the intervention using X

Indexed as

endotoxinhemoperfusionpolymyxinseptic shock

Identifiers

PMID37511635
PMCPMC10381630

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.