Evidence map›Paper›PMID 37511630›Full record

ArticleInternational journal of molecular sciences2023

Nanocellulose Sponges Containing Antibacterial Basil Extract.

Gabriela Mădălina Oprică, Denis Mihaela Panaitescu, Catalina Diana Usurelu, George Mihai Vlăsceanu, Paul Octavian Stanescu, Brandusa Elena Lixandru, Valentin Vasile, Augusta Raluca Gabor, Cristian-Andi Nicolae, Marius Ghiurea and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gabriela Mădălina OpricăNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.
Denis Mihaela PanaitescuNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0003-3352-0929
Catalina Diana UsureluNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.
George Mihai VlăsceanuFaculty of Chemical Engineering and Biotechnology, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Paul Octavian StanescuFaculty of Chemical Engineering and Biotechnology, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Brandusa Elena LixandruCantacuzino National Medical-Military Institute for Research and Development, 103 Spl. Independentei, 050096 Bucharest, Romania.
Valentin VasileCantacuzino National Medical-Military Institute for Research and Development, 103 Spl. Independentei, 050096 Bucharest, Romania.
Augusta Raluca GaborNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0003-3785-2314
Cristian-Andi NicolaeNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.
Marius GhiureaNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0003-1970-0552
Adriana Nicoleta FroneNational Institute for Research and Development in Chemistry and Petrochemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.ORCID 0000-0001-6232-886X

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P2-2.1-PED-2021-2559 (BIOPLASM) contract 632PED/2022
6 · The paper itself

Abstract

Nanocellulose (NC) is a valuable material in tissue engineering, wound dressing, and drug delivery, but its lack of antimicrobial activity is a major drawback for these applications. In this work, basil ethanolic extract (BE) and basil seed mucilage (BSM) were used to endow nanocellulose with antibacterial activity. NC/BE and NC/BE/BSM sponges were obtained from nanocellulose suspensions and different amounts of BE and BSM after freeze-drying. Regardless of the BE or BSM content, the sponges started to decompose at a lower temperature due to the presence of highly volatile active compounds in BE. A SEM investigation revealed an opened-cell structure and nanofibrillar morphology for all the sponges, while highly impregnated nanofibers were observed by SEM in NC/BE sponges with higher amounts of BE. A quantitative evaluation of the porous morphology by microcomputer tomography showed that the open porosity of the sponges varied between 70% and 82%, being lower in the sponges with higher BE/BSM content due to the impregnation of cellulose nanofibers with BE/BSM, which led to smaller pores. The addition of BE increased the specific compression strength of the NC/BE sponges, with a higher amount of BE having a stronger effect. A slight inhibition of

Indexed as

Ocimum basilicumStaphylococcus aureusAnti-Bacterial AgentsPlant ExtractsAnti-Bacterial Agentsbasil extractPlant Extractsantibacterialbasil extractcellulosemicrostructurenanofibersporosity

Identifiers

PMID37511630
PMCPMC10380770

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.