Evidence map›Paper›PMID 37511538›Full record

ArticleInternational journal of molecular sciences2023

Photo-Methionine, Azidohomoalanine and Homopropargylglycine Are Incorporated into Newly Synthesized Proteins at Different Rates and Differentially Affect the Growth and Protein Expression Levels of Auxotrophic and Prototrophic

Tomas Jecmen, Roman Tuzhilkin, Miroslav Sulc

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Expanding the methionine toolkit:bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tomas JecmenDepartment of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 43 Prague, Czech Republic.ORCID 0000-0002-1137-9808
Roman TuzhilkinDepartment of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 43 Prague, Czech Republic.
Miroslav SulcDepartment of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 43 Prague, Czech Republic.ORCID 0000-0002-2659-0489
Charles University · CZ

Funding

Charles University Grant Agency 1538119Czech Science Foundation 20-28126SMinistry of Education SVV 260 691/2023
6 · The paper itself

Abstract

Residue-specific incorporation of non-canonical amino acids (ncAAs) introduces bio-orthogonal functionalities into proteins. As such, this technique is applied in protein characterization and quantification. Here, we studied protein expression with three methionine analogs, namely photo-methionine (pMet), azidohomoalanine (Aha) and homopropargylglycine (Hpg), in prototrophic

Indexed as

Escherichia coliMethionineAlanineAlkynesAmino AcidsGlycineProteinsRacemethionineAlanineAlkynesAmino AcidsazidohomoalanineGlycinehomopropargylglycineMethionineProteinsRacemethionineazidohomoalaninebio-orthogonal amino acid global substitutionE. colihomopropargylglycinenon-canonical amino-acid-containing proteinsphoto-methionine

Identifiers

PMID37511538
PMCPMC10380393
OpenAlexW4385161897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.