Evidence map›Paper›PMID 37511537›Full record

ArticleInternational journal of molecular sciences2023

Long-Term Treatment with Cannabidiol-Enriched

Andrey F L Aguiar, Raquel M P Campos, Alinny R Isaac, Yolanda Paes-Colli, Virgínia M Carvalho, Luzia S Sampaio, Ricardo A de Melo Reis

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. The Use of Compounds Derived fromInternational journal of molecular sciences · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrey F L AguiarInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro 21941902, Brazil.ORCID 0000-0003-3914-4549
Raquel M P CamposInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro 21941902, Brazil.ORCID 0000-0002-6156-135X
Alinny R IsaacInstitute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro 21941902, Brazil.
Yolanda Paes-ColliInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro 21941902, Brazil.ORCID 0000-0001-9275-1175
Virgínia M CarvalhoFaculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro 21941902, Brazil.
Luzia S SampaioInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro 21941902, Brazil.
Ricardo A de Melo ReisInstitute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro 21941902, Brazil.ORCID 0000-0001-9689-4085
Universidade Federal do Rio de Janeiro · BR

Funding

Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.360870/2019-00Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E- 26/202.997/2019; E-26/202.668/2018; E-26/010.002215/2019; E-26/204.253/2021Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional 426342/2018-6; 312157/2016-9National Council for Scientific and Technological Development 426406/2018-4Serrapilheira Institute Serra-1709-18891
6 · The paper itself

Abstract

The endocannabinoid system (eCS) is widely distributed in mammalian tissues and it is classically formed by cannabinoid receptors, endogenous bioactive lipids and its synthesis and degradation enzymes. Due to the modulatory role of eCS in synaptic activity in the Central Nervous System (CNS), phytocannabinoids have been increasingly used for the treatment of neurological disorders, even though little is known in terms of the long-term effect of these treatments on CNS development, mainly in the timeframe that comprises childhood and adolescence. Furthermore, an increased number of clinical trials using full-spectrum

Indexed as

CannabidiolCannabisHallucinogensAnimalsCannabinoid Receptor AgonistsEndocannabinoidsHippocampusMammalsPlant ExtractsRatsRats, WistarCannabidiolCannabinoid Receptor AgonistsEndocannabinoidsHallucinogensPlant ExtractsCannabisendocannabinoid systemsynaptic changes

Identifiers

PMID37511537
PMCPMC10380262
OpenAlexW4385162018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.