ReviewInternational journal of molecular sciences2023
Current Review of Increasing Animal Health Threat of Per- and Polyfluoroalkyl Substances (PFAS): Harms, Limitations, and Alternatives to Manage Their Toxicity.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Review
- Distribution of poly- and perfluoroalkyl substances in pig liver and muscle: implications for food safety.Italian journal of food safety · 2026Article
- Differential prevalence of PFAS, PCBs and pesticides in liver of hunted game.Environmental science and pollution research international · 2026Article
- Analytical Tools for Understanding Molecular Level Interactions of Per- and Polyfluoroalkyl Substances (PFAS) with Sorbent Materials.Analytical chemistry · 2026Review
- Beyond persistence: SERS-driven strategies for PFAS detection and monitoring.Nano convergence · 2026Review
- Photocatalytic degradation of perfluorooctanoic acid under ambient conditions validated by duckweed as a sensitive ecotoxicity assay.Journal of hazardous materials. Organics · 2026Article
- An overview of the impact of PFAS on animals, humans, and the environment using a One Health approach.Environmental science and pollution research international · 2026Review
- Dental fluorosis in the European roe deer (Capreolus capreolus): A review of the pathological changes in the enamel of fluorotic cheek teeth and the abnormal pattern of dental wear in affected dentitions.Anatomical record (Hoboken, N.J. : 2007) · 2026Review
- Novel LC-MS/MS Method for Monitoring Perfluoroalkyl and Polyfluoroalkyl Substances in Companion Animal Blood Plasma and Serum: Environmental and Health Implications.International journal of veterinary science and medicine · 2026Article
- An investigation of per- and polyfluoroalkyl concentrations in dogs and cats with endocrine disorders.Frontiers in veterinary science · 2026Article
- Compact high power, medium energy electron accelerator for treatment of per- and polyfluoroalkyl contamination in water.PloS one · 2026Article
- Development of a qualitative risk assessment for meat from wild boar from a One-Health perspective.EFSA journal. European Food Safety Authority · 2025Article
- Per- and polyfluoroalkyl substance concentrations during pregnancy and at birth and risk of childhood acute lymphoblastic leukemia.Environmental research · 2025Article
- Preliminary results from monitoring perfluoroalkyl substances contamination in the livers of broiler chickens raised in Italy.Italian journal of food safety · 2025Article
- PFAS Exposure, Mental Health, and Environmental Justice in the United States: Impacts on Marginalized Communities.International journal of environmental research and public health · 2025Review
- Single-cell RNA sequencing reveals tissue-specific transcriptomic changes induced by perfluorooctanesulfonic acid (PFOS) in larval zebrafish (Danio rerio).Journal of hazardous materials · 2025Article
- Article
- Gallium Resistance inApplied microbiology (Basel, Switzerland) · 2025Article
- Review
- Advances in waste-derived functional materials for PFAS remediation.Biodegradation · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perfluorinated and polyfluorinated alkyl substances (PFAS), more than 4700 in number, are a group of widely used man-made chemicals that accumulate in living things and the environment over time. They are known as "forever chemicals" because they are extremely persistent in our environment and body. Because PFAS have been widely used for many decades, their presence is evident globally, and their persistence and potential toxicity create concern for animals, humans and environmental health. They can have multiple adverse health effects, such as liver damage, thyroid disease, obesity, fertility problems, and cancer. The most significant source of living exposure to PFAS is dietary intake (food and water), but given massive industrial and domestic use, these substances are now punctually present not only domestically but also in the outdoor environment. For example, livestock and wildlife can be exposed to PFAS through contaminated water, soil, substrate, air, or food. In this review, we have analyzed and exposed the characteristics of PFAS and their various uses and reported data on their presence in the environment, from industrialized to less populated areas. In several areas of the planet, even in areas far from large population centers, the presence of PFAS was confirmed, both in marine and terrestrial animals (organisms). Among the most common PFAS identified are undoubtedly perfluorooctanesulfonate (PFOS) and perfluorooctanoic acid (PFOA), two of the most widely used and, to date, among the most studied in terms of toxicokinetics and toxicodynamics. The objective of this review is to provide insights into the toxic potential of PFAS, their exposure, and related mechanisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.