Evidence map›Paper›PMID 37511415›Full record

ArticleInternational journal of molecular sciences2023

Suppression of TGFβ-Induced Interleukin-6 Secretion by Sinulariolide from Soft Corals through Attenuation of the p38-NF-kB Pathway in Carcinoma Cells.

Jenq-Lin Yang, Weng-Ling Lin, Shun-Ban Tai, Yi-Siang Ciou, Chih-Ling Chung, Jih-Jung Chen, Pei-Feng Liu, Ming-Wei Lin, Chun-Lin Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Analysis of Cembrane-Type Diterpenoids from Cultured Soft CoralInternational journal of molecular sciences · 2025
    Article
  4. TGF-β induces excessive pulmonary IL-6 secretion in cystic fibrosis via PI3K.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  5. Article
  6. Androgen Signaling in Prostate Cancer: When a Friend Turns Foe.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Jenq-Lin YangInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.ORCID 0000-0002-9897-8087
Weng-Ling LinDepartment of Pathology, Kaohsiung Armed Forces General Hospital, Kaohsiung 80284, Taiwan.
Shun-Ban TaiDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.
Yi-Siang CiouDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.
Chih-Ling ChungDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0002-1152-3224
Jih-Jung ChenDepartment of Pharmacy, School of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-5680-9533
Pei-Feng LiuDepartment of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung 80756, Taiwan.
Ming-Wei LinDepartment of Medical Research, E-Da Hospital/E-Da Cancer Hospital, Kaohsiung 82445, Taiwan.
Chun-Lin ChenDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0003-1519-2642
National Sun Yat-sen University · TWE-Da Hospital · TWKaohsiung Armed Forces General Hospital · TWKaohsiung Chang Gung Memorial Hospital · TWKaohsiung Medical University · TWNational Yang Ming Chiao Tung University · TW

Funding

Kaohsiung Chang Gung Memorial Hospital Research Project CMRPG8N0061Ministry of Science and Technology of Taiwan 107-2320-B-110-002-MY3Ministry of Science and Technology of Taiwan 110-2320-B-110-004Ministry of Science and Technology of Taiwan 111-2320-B-110-008The Kaohsiung Armed Forces General Hospital Research Project KAFGH-D-109036The Zuoying Branch of Kaohsiung Armed Forces General Hospital Research Project KAFGH-ZY-A-112019
6 · The paper itself

Abstract

Sinulariolide (SC-1) is a natural product extracted from the cultured-type soft coral

Indexed as

AnthozoaCarcinomaAnimalsDiterpenesInterleukin-6NF-kappa BTransforming Growth Factor betaDiterpenesInterleukin-6NF-kappa BsinulariolideTransforming Growth Factor betainterleukin-6sinulariolideTGF-β

Identifiers

PMID37511415
PMCPMC10380600
OpenAlexW4384821289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.