Evidence map›Paper›PMID 37511294›Full record

ArticleInternational journal of molecular sciences2023

Investigating the Prevalence of RNA-Binding Metabolic Enzymes in

Thomas Klein, Franziska Funke, Oliver Rossbach, Gerhard Lehmann, Michael Vockenhuber, Jan Medenbach, Beatrix Suess, Gunter Meister, Patrick Babinger

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. iScience · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Thomas KleinInstitute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, D-93040 Regensburg, Germany.
Franziska FunkeInstitute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, D-93040 Regensburg, Germany.
Oliver RossbachInstitute of Biochemistry, Faculty of Biology and Chemistry, University of Giessen, D-35392 Giessen, Germany.ORCID 0000-0002-1172-0359
Gerhard LehmannInstitute of Biochemistry, Genetics and Microbiology, Regensburg Center for Biochemistry, University of Regensburg, D-93040 Regensburg, Germany.
Michael VockenhuberCentre for Synthetic Biology, Technical University of Darmstadt, D-64287 Darmstadt, Germany.
Jan MedenbachInstitute of Biochemistry, Genetics and Microbiology, Regensburg Center for Biochemistry, University of Regensburg, D-93040 Regensburg, Germany.
Beatrix SuessCentre for Synthetic Biology, Technical University of Darmstadt, D-64287 Darmstadt, Germany.
Gunter MeisterInstitute of Biochemistry, Genetics and Microbiology, Regensburg Center for Biochemistry, University of Regensburg, D-93040 Regensburg, Germany.ORCID 0000-0002-2098-9923
Patrick BabingerInstitute of Biophysics and Physical Biochemistry, Regensburg Center for Biochemistry, University of Regensburg, D-93040 Regensburg, Germany.ORCID 0000-0002-7490-6732
University of Regensburg · DETechnische Universität Darmstadt · DEJustus-Liebig-Universität Gießen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An open research field in cellular regulation is the assumed crosstalk between RNAs, metabolic enzymes, and metabolites, also known as the REM hypothesis. High-throughput assays have produced extensive interactome data with metabolic enzymes frequently found as hits, but only a few examples have been biochemically validated, with deficits especially in prokaryotes. Therefore, we rationally selected nineteen

Indexed as

Escherichia coliPrevalencemetabolic enzymesMS2 phageprokaryotesquinone oxidoreductaseREM hypothesisRNA-binding proteinSELEXunconventional RNA binding

Identifiers

PMID37511294
PMCPMC10380284
OpenAlexW4384557591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.