Evidence map›Paper›PMID 37511246›Full record

ArticleInternational journal of molecular sciences2023

6-Oxofurostane and (iso)Spirostane Types of Saponins in

Bharathi Avula, Ji-Yeong Bae, Jongmin Ahn, Kumar Katragunta, Yan-Hong Wang, Mei Wang, Yongsoo Kwon, Ikhlas A Khan, Amar G Chittiboyina

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Bharathi AvulaNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Ji-Yeong BaeNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0003-0543-9138
Jongmin AhnNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0002-9362-7384
Kumar KatraguntaNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0002-8787-4602
Yan-Hong WangNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0003-3341-8991
Mei WangNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0003-3686-4292
Yongsoo KwonNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Ikhlas A KhanNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0001-5464-4643
Amar G ChittiboyinaNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0002-7047-5373
University of Mississippi · US

Funding

FDA HHS U01 FD004246
6 · The paper itself

Abstract

Identifying novel phytochemical secondary metabolites following classical pharmacognostic investigations is tedious and often involves repetitive chromatographic efforts. During the past decade, Ultra-High Performance Liquid Chromatography-Quadrupole Time of Flight-Tandem Mass Spectrometry (UHPLC-QToF-MS/MS), in combination with molecular networking, has been successfully demonstrated for the rapid dereplication of novel natural products in complex mixtures. As a logical application of such innovative tools in botanical research, more than 40 unique 3-oxy-, 3, 6-dioxy-, and 3, 6, 27-trioxy-steroidal saponins were identified in aerial parts and rhizomes of botanically verified

Indexed as

SaponinsSmilaxChromatography, High Pressure LiquidPlant ExtractsTandem Mass SpectrometryTissue DistributionPlant ExtractsSaponinshyphenated methodsliquid chromatographymolecular networkingphytochemicalssteroidal saponins

Identifiers

PMID37511246
PMCPMC10380369
OpenAlexW4384557335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.