Evidence map›Paper›PMID 37511227›Full record

ArticleInternational journal of molecular sciences2023

Effects of Angiotensin 1-7 and Mas Receptor Agonist on Renal System in a Rat Model of Heart Failure.

Ravit Cohen-Segev, Omri Nativ, Safa Kinaneh, Doron Aronson, Aviva Kabala, Shadi Hamoud, Tony Karram, Zaid Abassi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. The RAAS Goodfellas in Cardiovascular System.Journal of clinical medicine · 2023
    Review
  7. Neurohumoral Activation in Heart Failure.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ravit Cohen-SegevDepartment of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.
Omri NativDepartment of Urology, Rambam Health Center, Haifa 3109601, Israel.
Safa KinanehDepartment of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.
Doron AronsonCardiology, Rambam Health Care Campus, Haifa 3109601, Israel.
Aviva KabalaDepartment of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.
Shadi HamoudDepartment of Internal Medicine E, Rambam Health Care Campus, Haifa 3109601, Israel.ORCID 0000-0003-1405-239X
Tony KarramVascular Surgery, Rambam Health Care Campus, Haifa 3109601, Israel.
Zaid AbassiDepartment of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.ORCID 0000-0002-7272-197X
Rambam Health Care Campus · ILTechnion – Israel Institute of Technology · IL

Funding

Israel Science Foundation 544/18
6 · The paper itself

Abstract

Congestive heart failure (CHF) is often associated with impaired kidney function. Over- activation of the renin-angiotensin-aldosterone system (RAAS) contributes to avid salt/water retention and cardiac hypertrophy in CHF. While the deleterious effects of angiotensin II (Ang II) in CHF are well established, the biological actions of angiotensin 1-7 (Ang 1-7) are not fully characterized. In this study, we assessed the acute effects of Ang 1-7 (0.3, 3, 30 and 300 ng/kg/min, IV) on urinary flow (UF), urinary Na

Indexed as

Heart FailureAngiotensin IAngiotensin IIAnimalsCardiomegalyKidneyPeptide FragmentsRatsRenin-Angiotensin SystemAngiotensin Iangiotensin I (1-7)Angiotensin IIPeptide FragmentsACE2angiotensin 1-7heart failurekidneyMasR

Identifiers

PMID37511227
PMCPMC10380355
OpenAlexW4384339215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.