Evidence map›Paper›PMID 37511164›Full record

ArticleInternational journal of molecular sciences2023

The Influence of Single Nucleotide Polymorphisms on Vitamin D Receptor Protein Levels and Function in Chronic Liver Disease.

Evanthia Tourkochristou, Efthymios P Tsounis, Haralampos Tzoupis, Ioanna Aggeletopoulou, Aggeliki Tsintoni, Theoni Lourida, Georgia Diamantopoulou, Konstantinos Zisimopoulos, Theodora Kafentzi, Anne-Lise de Lastic and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. The Role of Vitamin D and Vitamin D Receptor in Sepsis.Current issues in molecular biology · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Evanthia TourkochristouDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.
Efthymios P TsounisDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0003-2797-5070
Haralampos TzoupisDepartment of Chemistry, University of Patras, 26504 Patras, Greece.ORCID 0000-0002-1534-2762
Ioanna AggeletopoulouDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0003-4489-1485
Aggeliki TsintoniDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.
Theoni LouridaDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0002-1332-6013
Georgia DiamantopoulouDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.
Konstantinos ZisimopoulosDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.
Theodora KafentziDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.
Anne-Lise de LasticDivision of Hematology, Department of Internal Medicine, Medical School, University of Patras, 26504 Patras, Greece.ORCID 0000-0002-3152-4777
Maria RodiDivision of Hematology, Department of Internal Medicine, Medical School, University of Patras, 26504 Patras, Greece.ORCID 0000-0001-6578-0851
Theodore TseliosDepartment of Chemistry, University of Patras, 26504 Patras, Greece.
Konstantinos ThomopoulosDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.
Athanasia MouzakiDivision of Hematology, Department of Internal Medicine, Medical School, University of Patras, 26504 Patras, Greece.ORCID 0000-0001-5548-7002
Christos TriantosDivision of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0003-3094-8209
University of Patras · GR

Funding

C.CARATHEODORI Program from the Research Committee of the University of Patras 80672GILEAD-ASKLEPIOS 80450
6 · The paper itself

Abstract

Single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene have been associated with chronic liver disease. We investigated the role of VDR SNPs on VDR protein levels and function in patients with chronic liver disease. VDR expression levels were determined in peripheral T lymphocytes (CD3+VDR+), monocytes (CD14+VDR+), and plasma from patients (

Indexed as

Hepatitis C, ChronicLiver CirrhosisCase-Control StudiesGenetic Predisposition to DiseaseGenotypeHumansPolymorphism, Single NucleotideReceptors, CalcitriolReceptors, Calcitriolgene expressionHCVliver cirrhosisproteinSNPsVDR

Identifiers

PMID37511164
PMCPMC10380285
OpenAlexW4384341240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.