Evidence map›Paper›PMID 37511059›Full record

ReviewInternational journal of molecular sciences2023

Unravelling the Role of P300 and TMPRSS2 in Prostate Cancer: A Literature Review.

Charitomeni Gioukaki, Alexandros Georgiou, Lydia Evangelia Gkaralea, Christos Kroupis, Andreas C Lazaris, Christos Alamanis, Georgia Eleni Thomopoulou

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Charitomeni GioukakiFirst Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Alexandros GeorgiouFirst Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Lydia Evangelia GkaraleaDepartment of Medical Oncology, Agii Anargiri Cancer Hospital, 14564 Athens, Greece.
Christos KroupisDepartment of Clinical Biochemistry, Attikon University Hospital, National and Kapodistrian University of Athens, 12461 Athens, Greece.ORCID 0000-0002-5876-2599
Andreas C LazarisFirst Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-8118-7780
Christos Alamanis1st Urology Department, Laiko Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Georgia Eleni ThomopoulouCytopathology Department, Attikon University Hospital, National and Kapodistrian University of Athens, 12461 Athens, Greece.
National and Kapodistrian University of Athens · GRHospital Agioi Anargyroi · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is one of the most common malignant diseases in men, and it contributes significantly to the increased mortality rate in men worldwide. This study aimed to review the roles of p300 and TMPRSS2 (transmembrane protease, serine 2) in the AR (androgen receptor) pathway as they are closely related to the development and progression of prostate cancer. This paper represents a library-based study conducted by selecting the most suitable, up-to-date scientific published articles from online journals. We focused on articles that use similar techniques, particularly those that use prostate cancer cell lines and immunohistochemical staining to study the molecular impact of p300 and TMPRSS2 in prostate cancer specimens. The

Indexed as

p300-CBP Transcription FactorsProstatic NeoplasmsSerine EndopeptidasesBiopsyHumansMaleOncogene Proteins, Fusionp300-CBP-Associated FactorProstateTranscriptional Regulator ERGOncogene Proteins, Fusionp300-CBP-Associated Factorp300-CBP Transcription FactorsSerine EndopeptidasesTMPRSS2 protein, humanTranscriptional Regulator ERGandrogen receptorGleason scoremolecular pathologyp300precision medicineprostate cancerTMPRSS2

Identifiers

PMID37511059
PMCPMC10379122
OpenAlexW4383954904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.