Evidence map›Paper›PMID 37510956›Full record

ArticleJournal of clinical medicine2023

Long-Term Survival among Octogenarians Undergoing Aortic Valve Replacement with or without Simultaneous Coronary Artery Bypass Grafting: A 22-Year Tertiary Single-Center Experience.

Hannah Masraf, Davorin Sef, Sirr Ling Chin, Gabriel Hunduma, Vladimir Trkulja, Szabolcs Miskolczi, Theodore Velissaris, Suvitesh Luthra

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Hannah MasrafWessex Cardiothoracic Centre, University Hospital Southampton, Southampton SO16 6YD, UK.
Davorin SefWessex Cardiothoracic Centre, University Hospital Southampton, Southampton SO16 6YD, UK.ORCID 0000-0001-5053-3815
Sirr Ling ChinWessex Cardiothoracic Centre, University Hospital Southampton, Southampton SO16 6YD, UK.
Gabriel HundumaWessex Cardiothoracic Centre, University Hospital Southampton, Southampton SO16 6YD, UK.
Vladimir TrkuljaSchool of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Szabolcs MiskolcziWessex Cardiothoracic Centre, University Hospital Southampton, Southampton SO16 6YD, UK.
Theodore VelissarisWessex Cardiothoracic Centre, University Hospital Southampton, Southampton SO16 6YD, UK.
Suvitesh LuthraWessex Cardiothoracic Centre, University Hospital Southampton, Southampton SO16 6YD, UK.
University Hospital Southampton NHS Foundation Trust · GBUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of concomitant coronary artery bypass grafting (CABG) on aortic valve replacement (AVR) in octogenarians is still debated. We analyzed the characteristics and long-term survival of octogenarians undergoing isolated AVR and AVR + CABG.

methodsAll octogenarians who consecutively underwent AVR with or without concomitant CABG at our tertiary cardiac center between 2000 and 2022 were included. Patients with redo, emergent, or any other concomitant procedures were excluded. The primary endpoints were 30-day and long-term survival. The secondary endpoints were early postoperative outcomes and determinants of long-term survival. Univariable and multivariable logistic regression analyses were performed to identify independent predictors of 30-day mortality, and Cox regression analysis was performed for predictors of adverse long-term survival.

resultsA total of 1011 patients who underwent AVR (83.0 [81.0-85.0] years, 42.0% males) and 1055 with AVR + CABG (83.0 [81.2-85.4] years, 66.1% males) were included in our study. Survival at 30 days and at 1, 3, and 5 years in the AVR group was 97.9%, 91.5%, 80.5%, and 66.2%, respectively, while in the AVR + CABG group it was 96.2%, 89.6%, 77.7%, and 64.7%, respectively. There was no significant difference in median postoperative survival between the AVR and AVR + CABG groups (7.1 years [IQR: 6.7-7.5] vs. 6.6 years [IQR: 6.3-7.2], respectively,

conclusionsThe long-term survival of octogenarians who underwent AVR or AVR + CABG was similar and was not affected by adding concomitant CABG. However, octogenarians who underwent concomitant CABG with AVR had significantly higher in-hospital mortality. Each decision should be discussed within the heart team.

Indexed as

aortic valve replacementcoronary artery bypass graftinglong-term survivaloctogenarians

Identifiers

PMID37510956
PMCPMC10381828
OpenAlexW4385213598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.