Evidence map›Paper›PMID 37510392›Full record

SynthesisGenes2023

Tumor Necrosis Factor-α G-308A Polymorphism and Sporadic IgA Nephropathy: A Meta-Analysis Using a Genetic Model-Free Approach.

Maria Tziastoudi, Ioanna Chronopoulou, Georgios Pissas, Christos Cholevas, Theodoros Eleftheriadis, Ioannis Stefanidis

Open access · goldAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria TziastoudiDepartment of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0002-7206-2716
Ioanna ChronopoulouDepartment of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.
Georgios PissasDepartment of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.
Christos CholevasFirst Department of Ophthalmology, Faculty of Health Sciences, Aristotle University of Thessaloniki School of Medicine, AHEPA Hospital, 54636 Thessaloniki, Greece.ORCID 0000-0002-1517-8691
Theodoros EleftheriadisDepartment of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0001-9302-1633
Ioannis StefanidisDepartment of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.
University of Thessaly · GRAristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor necrosis factor-α (TNF-α) is a potent pro-inflammatory cytokine, involved in the pathogenesis and progression of immunoglobulin A nephropathy (IgAN). A bi-allelic polymorphism in the promoter region, at position -308 (G/A) of the

Indexed as

Glomerulonephritis, IGATumor Necrosis Factor-alphaGenetic Association StudiesHumansPolymorphism, GeneticTNF protein, humanTumor Necrosis Factor-alphaimmunoglobulin A nephropathy (IgAN)meta-analysispolymorphismTNF-αtumor necrosis factor-α

Identifiers

PMID37510392
PMCPMC10378840
OpenAlexW4385226365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.