Evidence map›Paper›PMID 37510205›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Diagnostic Role of Native T1 Mapping Compared to Conventional Magnetic Resonance Techniques in Cardiac Disease in a Real-Life Cohort.

Giovanni Donato Aquaro, Silvia Monastero, Giancarlo Todiere, Andrea Barison, Carmelo De Gori, Crysanthos Grigoratos, Maria Luisa Parisella, Lorenzo Faggioni, Dania Cioni, Riccardo Lencioni and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Quantitative imaging in medicine and surgery · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Giovanni Donato AquaroAcademic Radiology Unit, Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-0915-915X
Silvia MonasteroGabriele Monasterio CNR-Tuscany Foundation, 56127 Pisa, Italy.
Giancarlo TodiereAcademic Radiology Unit, Department of Translational Research and of New Technology in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Andrea BarisonAcademic Radiology Unit, Department of Translational Research and of New Technology in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-9042-340X
Carmelo De GoriAcademic Radiology Unit, Department of Translational Research and of New Technology in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-6051-3698
Crysanthos GrigoratosAcademic Radiology Unit, Department of Translational Research and of New Technology in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Maria Luisa ParisellaGabriele Monasterio CNR-Tuscany Foundation, 56127 Pisa, Italy.
Lorenzo FaggioniGabriele Monasterio CNR-Tuscany Foundation, 56127 Pisa, Italy.ORCID 0000-0001-5262-4489
Dania CioniAcademic Radiology Unit, Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-5120-886X
Riccardo LencioniAcademic Radiology Unit, Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.
Emanuele NeriGabriele Monasterio CNR-Tuscany Foundation, 56127 Pisa, Italy.ORCID 0000-0001-7950-4559
University of Pisa · ITFondazione Toscana Gabriele Monasterio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to compare native T1 mapping to conventional late gadolinium enhancement (LGE) and T2-STIR techniques in a cohort of consecutive patients undergoing cardiac MRI (CMR). CMR was performed in 323 patients, 206 males (64%), mean age 54 ± 8 years, and in 27 age- and sex- matched healthy controls. In T2-STIR images, myocardial hyperintensity suggesting edema was found in 41 patients (27%). LGE images were positive in 206 patients (64%). T1 mapping was abnormal in 171 (49%). In 206 patients (64%), a matching between LGE and native T1 was found. T1 was abnormal in 32 out of 41 (78%) with edema in T2-STIR images. Overall, LGE and/or T2-STIR were abnormal in 209 patients, whereas native T1 was abnormal in 154 (52%). Conventional techniques and T1 mapping were concordant in 208 patients (64%). In 39 patients, T1 mapping was positive despite negative conventional techniques (12%). T1 mapping was able in conditions with diffuse myocardial damage such as cardiac amyloidosis, scleroderma, and Fabry disease (additive role in 42%). In contrast, T1 mapping was less effective in cardiac disease with regional distribution of myocardial damage such as myocardial infarction, HCM, and myocarditis. In conclusion, conventional LGE/T2-STIR and T1 mapping are complementary techniques and should be used together in every CMR examination.

Indexed as

cardiac magnetic resonancelate gadolinium enhancementT1 mappingT2-STIR

Identifiers

PMID37510205
PMCPMC10377876
OpenAlexW4385251401

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.