Evidence map›Paper›PMID 37510197›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Electric Bioimpedance Sensing for the Detection of Head and Neck Squamous Cell Carcinoma.

Andrea Luigi Camillo Carobbio, Zhuoqi Cheng, Tomaso Gianiorio, Francesco Missale, Stefano Africano, Alessandro Ascoli, Marco Fragale, Marta Filauro, Filippo Marchi, Luca Guastini and 5 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andrea Luigi Camillo CarobbioIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-0919-971X
Zhuoqi ChengMaersk Mc-Kinney Moller Institute, University of Southern Denmark, 5230 Odense, Denmark.
Tomaso GianiorioDepartment of Advanced Robotics, Istituto Italiano di Tecnologia, 16163 Genova, Italy.
Francesco MissaleIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-5357-5348
Stefano AfricanoIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Alessandro AscoliIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-7375-5581
Marco FragaleIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Marta FilauroIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-6000-3006
Filippo MarchiIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-7997-964X
Luca GuastiniIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Francesco MoraIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Giampiero ParrinelloIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Frank Rikki Mauritz CanevariIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.ORCID 0000-0002-1821-7262
Giorgio PerettiIRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
Leonardo S MattosDepartment of Advanced Robotics, Istituto Italiano di Tecnologia, 16163 Genova, Italy.ORCID 0000-0002-8511-9144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The early detection of head and neck squamous cell carcinoma (HNSCC) is essential to improve patient prognosis and enable organ and function preservation treatments. The objective of this study is to assess the feasibility of using electrical bioimpedance (EBI) sensing technology to detect HNSCC tissue. A prospective study was carried out analyzing tissue from 46 patients undergoing surgery for HNSCC. The goal was the correct identification of pathologic tissue using a novel needle-based EBI sensing device and AI-based classifiers. Considering the data from the overall patient cohort, the system achieved accuracies between 0.67 and 0.93 when tested on tissues from the mucosa, skin, muscle, lymph node, and cartilage. Furthermore, when considering a patient-specific setting, the accuracy range increased to values between 0.82 and 0.95. This indicates that more reliable results may be achieved when considering a tissue-specific and patient-specific tissue assessment approach. Overall, this study shows that EBI sensing may be a reliable technology to distinguish pathologic from healthy tissue in the head and neck region. This observation supports the continuation of this research on the clinical use of EBI-based devices for early detection and margin assessment of HNSCC.

Indexed as

cancer detectionclassifierelectrical bioimpedancehead and neck cancermachine learningsquamous cell carcinoma

Identifiers

PMID37510197
PMCPMC10377945

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.