Evidence map›Paper›PMID 37510179›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Contrast-Enhanced Computed Tomography and Laboratory Parameters as Non-Invasive Diagnostic Markers of Pancreatic Fibrosis.

Igor E Khatkov, Dmitry S Bordin, Konstantin A Lesko, Elena A Dubtsova, Nikolay S Karnaukhov, Maria A Kiriukova, Nadezhda V Makarenko, Alexey S Dorofeev, Irina V Savina, Diana A Salimgereeva and 2 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Igor E KhatkovA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Dmitry S BordinA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.ORCID 0000-0003-2815-3992
Konstantin A LeskoA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.ORCID 0000-0001-9814-0172
Elena A DubtsovaA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Nikolay S KarnaukhovA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Maria A KiriukovaA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Nadezhda V MakarenkoA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Alexey S DorofeevA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Irina V SavinaA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Diana A SalimgereevaA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.ORCID 0000-0001-9742-3955
Elena I ShuryginaA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Ludmila V VinokurovaA.S. Loginov Moscow Clinical Scientific Center, 111123 Moscow, Russia.
Moscow Clinical Scientific Center · RUMoscow State University of Medicine and Dentistry · RU

Funding

The autonomous non-profit organization "Moscow Center for Innovative Technologies in Healthcare" of the Moscow Healthcare Department 2412-21/22
6 · The paper itself

Abstract

Pancreatic fibrosis (PF) is a part of the pathogenesis in most pancreatic disorders and plays a crucial role in chronic pancreatitis development. The aim of our study was to investigate a relationship between PF grade and signs in resected pancreatic specimens, and the results of both multidetector computed tomography (MDCT) post-processing parameters and fibronectin (FN), hyaluronic acid (HA), matrix metalloproteinase (MMP)-1, and MMP-9 serum levels. The examination results of 74 patients were analyzed. The unenhanced pancreas density (UPD) value and contrast enhancement ratio (CER) showed statistically significant differences in groups with peri- and intralobular fibrosis grades, an integrative index of fibrosis, inflammation in pancreatic tissue, and pancreatic duct epithelium metaplasia, while the normalized contrast enhancement ratio in the venous phase (NCER VP) significantly differed with the perilobular fibrosis grade, integrative fibrosis index, and inflammation (

Indexed as

attenuationchronic pancreatitiscomputed tomographyfibronectinhyaluronic acidpancreatic fibrosis

Identifiers

PMID37510179
PMCPMC10377847
OpenAlexW4385214353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.