Evidence map›Paper›PMID 37510102›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Appendiceal Signet Ring Cell Carcinoma: An Atypical Cause of Acute Appendicitis-A Case Study and Review of Current Knowledge.

Branko Andjelkovic, Bojan Stojanovic, Milica Dimitrijevic Stojanovic, Bojan Milosevic, Aleksandar Cvetkovic, Marko Spasic, Stefan Jakovljevic, Danijela Cvetkovic, Bojana S Stojanovic, Danijela Milosev and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Branko AndjelkovicDepartment of General Surgery, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.
Bojan StojanovicDepartment of General Surgery, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0001-6115-612X
Milica Dimitrijevic StojanovicDepartment of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Bojan MilosevicDepartment of General Surgery, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.
Aleksandar CvetkovicDepartment of General Surgery, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.
Marko SpasicDepartment of General Surgery, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0001-7144-1696
Stefan JakovljevicDepartment of General Surgery, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia.
Danijela CvetkovicDepartment of Genetics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0001-7767-1345
Bojana S StojanovicDepartment of Pathophysiology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Danijela MilosevDepartment of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Minja MitrovicDepartment of Neurology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Vesna StankovicDepartment of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0002-8041-3491
University of Kragujevac · RSClinical Centre of Kragujevac · RS

Funding

Faculty of Medical Sciences at the University of Kragujevac, Serbia JP10/22
6 · The paper itself

Abstract

Appendiceal signet ring cell carcinoma (ASRCC) is a rare and aggressive form of appendiceal cancer, often presenting with nonspecific symptoms that overlap with acute appendicitis. Early diagnosis and appropriate management are crucial for improving patient outcomes in these rare malignancies. This case report and literature review aims to raise awareness among clinicians about ASRCC of the appendix as a cause of acute appendicitis and highlight the importance of considering this diagnosis in patients with atypical presentations or unexpected histopathological findings. We present a 65-year-old female patient with ASRCC who underwent successful surgical treatment and remains disease-free at the one-year follow-up. It also highlights the necessity of early detection and appropriate treatment in order to improve patient outcomes. In addition, a comprehensive literature review is provided, discussing the clinical presentation, histopathological characteristics, potential pathogenesis, treatment options, and prognosis of ASRCC.

Indexed as

acute appendicitisappendectomyappendixcase reportliterature reviewsignet ring cell carcinoma

Identifiers

PMID37510102
PMCPMC10378069
OpenAlexW4384341652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.