Evidence map›Paper›PMID 37509816›Full record

ArticleFoods (Basel, Switzerland)2023

Pressurized Liquid (PLE) Truffle Extracts Have Inhibitory Activity on Key Enzymes Related to Type 2 Diabetes (α-Glucosidase and α-Amylase).

Eva Tejedor-Calvo, Diego Morales, Laura Morillo, Laura Vega, Mercedes Caro, Fhernanda Ribeiro Smiderle, Marcello Iacomini, Pedro Marco, Cristina Soler-Rivas

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Eva Tejedor-CalvoDepartment of Production and Characterization of Novel Foods, Institute of Food Science Research-CIAL (UAM + CSIC), C/Nicolas Cabrera 9, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0001-5635-413X
Diego MoralesDepartment of Production and Characterization of Novel Foods, Institute of Food Science Research-CIAL (UAM + CSIC), C/Nicolas Cabrera 9, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0002-4600-6673
Laura MorilloDepartment of Production and Characterization of Novel Foods, Institute of Food Science Research-CIAL (UAM + CSIC), C/Nicolas Cabrera 9, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0003-0999-0357
Laura VegaDepartment of Production and Characterization of Novel Foods, Institute of Food Science Research-CIAL (UAM + CSIC), C/Nicolas Cabrera 9, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Mercedes CaroAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio, Spain.
Fhernanda Ribeiro SmiderleFaculdades Pequeno Príncipe, Curitiba 80230-020, PR, Brazil.
Marcello IacominiDepartment of Biochemistry and Molecular Biology, Federal University of Parana, Curitiba 81531-980, PR, Brazil.
Pedro MarcoDepartment of Forest Resources, Agrifood Research and Technology Centre of Aragon (CITA), Agrifood Institute of Aragón-IA2 (CITA-Zaragoza University), Av. Montañana 930, 50059 Zaragoza, Spain.ORCID 0000-0003-3384-7534
Cristina Soler-RivasDepartment of Production and Characterization of Novel Foods, Institute of Food Science Research-CIAL (UAM + CSIC), C/Nicolas Cabrera 9, Campus de Cantoblanco, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Instituto de Investigación en Ciencias de la Alimentación · ESEuskadiko Parke Teknologikoa · ESCentro de Investigación y Tecnología Agroalimentaria de Aragón · ESUniversidad Complutense de Madrid · ESUniversidade Federal do Paraná · BR

Funding

European Union Project number 101007623fellowship Ibercaja-CAI Estancias de Investigación CA 1/20
6 · The paper itself

Abstract

An optimized PLE method was applied to several truffle species using three different solvent mixtures to obtain bioactive enriched fractions. The pressurized water extracts contained mainly (1 → 3),(1 → 6)-β-D-glucans, chitins, and heteropolymers with galactose and mannose in their structures. The ethanol extracts included fatty acids and fungal sterols and others such as brassicasterol and stigmasterol, depending on the species. They also showed a different fatty acid lipid profile depending on the solvent utilized and species considered. Ethanol:water extracts showed interesting lipids and many phenolic compounds; however, no synergic extraction of compounds was noticed. Some of the truffle extracts were able to inhibit enzymes related to type 2 diabetes; pressurized water extracts mainly inhibited the α-amylase enzyme, while ethanolic extracts were more able to inhibit α-glucosidase.

Indexed as

amylaseantidiabeticergosterolfatty acidsglucosidasetrufflesβ-D-glucans

Identifiers

PMID37509816
PMCPMC10379309
OpenAlexW4384637778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.