Evidence map›Paper›PMID 37509606›Full record

ArticleBiomedicines2023

Interleukin 5 Receptor Subunit Alpha Expression as a Potential Biomarker in Patients with Nasal Polyposis.

David Hansoe Heredero-Jung, Sandra Elena-Pérez, Asunción García-Sánchez, Miguel Estravís, María Isidoro-García, Catalina Sanz, Ignacio Dávila

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David Hansoe Heredero-JungDepartment of Clinical Biochemistry, University Hospital of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-6631-9319
Sandra Elena-PérezDepartment of Clinical Biochemistry, University Hospital of Salamanca, 37007 Salamanca, Spain.
Asunción García-SánchezAllergic Disease Research Group IIMD-01, Institute for Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0002-9655-4918
Miguel EstravísAllergic Disease Research Group IIMD-01, Institute for Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0001-9788-4540
María Isidoro-GarcíaDepartment of Clinical Biochemistry, University Hospital of Salamanca, 37007 Salamanca, Spain.
Catalina SanzAllergic Disease Research Group IIMD-01, Institute for Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
Ignacio DávilaAllergic Disease Research Group IIMD-01, Institute for Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0001-8485-5513
Universidad de Salamanca · ESInstituto de Salud Carlos III · ES

Funding

Consejería de Educación de la Junta de Castilla y León co-funded by FEDER funds IES161P20funded by Instituto de Salud Carlos III and co-funded by the European Union PI20/00268Instituto de Salud Carlos III and European Regional Development Fund "A way to make Europe" IMP/00009Instituto de Salud Carlos III and European Union Next Generation EU, Mecanismo para la Recuperación y la Resiliencia MRR PMP22/00124Instituto de Salud Carlos III and European Union Next Generation EU, Mecanismo para la Recuperación y la Resiliencia MRR RD21/0002/0054MCIN/AEI/10.13039/501100011033 and by "ERDF A way of making Europe" by the "European Union" PID2021-125117OB-I00
6 · The paper itself

Abstract

Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP) affects the quality of life of patients suffering from it. The search for a suitable biomarker has been conducted over the last decades. Interleukin 5 receptor subunit alpha (IL-5Rα) involves the activation, maintenance, and survival of eosinophils, which are highly tied to chronic inflammatory processes of the airways, like asthma or CRSwNP. In this study, we evaluate the utility of

Indexed as

benralizumabbiomarkerchronic rhinosinusitisCRSwNPgene expressionIL5RAinterleukin-5nasal polyposispharmacogeneticsprecision medicine

Identifiers

PMID37509606
PMCPMC10377376
OpenAlexW4384202391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.