Evidence map›Paper›PMID 37509580›Full record

ArticleBiomedicines2023

Super-Resolution Imaging Reveals the Nanoscale Distributions of Dystroglycan and Integrin Itga7 in Zebrafish Muscle Fibers.

Komala Shivanna, Mary Astumian, Prakash Raut, Vinh-Nhan Ngo, Samuel T Hess, Clarissa Henry

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Komala ShivannaDepartment of Physics & Astronomy, University of Maine, 5709 Bennett Hall, Orono, ME 04469-5709, USA.
Mary AstumianSchool of Biology and Ecology, University of Maine, 217 Hitchner Hall, Orono, ME 04469-5751, USA.ORCID 0000-0002-0215-1772
Prakash RautDepartment of Physics & Astronomy, University of Maine, 5709 Bennett Hall, Orono, ME 04469-5709, USA.ORCID 0009-0000-2015-7396
Vinh-Nhan NgoDepartment of Physics & Astronomy, University of Maine, 5709 Bennett Hall, Orono, ME 04469-5709, USA.
Samuel T HessDepartment of Physics & Astronomy, University of Maine, 5709 Bennett Hall, Orono, ME 04469-5709, USA.
Clarissa HenrySchool of Biology and Ecology, University of Maine, 217 Hitchner Hall, Orono, ME 04469-5751, USA.ORCID 0000-0001-7204-9231
University of Maine · US

Funding

Mechanisms of NAD+ action during muscle development and homeostasis in a zebrafish dystroglycanopathy modelR01AR075836 · NIAMS · UNIVERSITY OF MAINE ORONO · PI HENRY, CLARISSA A · 2019 to 2023
$1.6M
Mechanism of Interaction between Influenza Hemagglutinin and Host Cell PhosphoinositidesR15GM139070 · NIGMS · UNIVERSITY OF MAINE ORONO · PI HESS, SAMUEL T · 2020 to 2020
$428k
Mechanism of Association between Influenza Hemagglutinin and the Host Cell Actin CytoskeletonR15GM116002 · NIGMS · UNIVERSITY OF MAINE ORONO · PI HESS, SAMUEL T · 2015 to 2015
$337k
NIAMS NIH HHS R01 AR075836NIGMS NIH HHS R15 GM116002NIGMS NIH HHS R15 GM139070NIH HHS R15GM116002NIH HHS R15GM139070NIH HHS RO1AR075836-01
6 · The paper itself

Abstract

Cell signaling is determined partially by the localization and abundance of proteins. Dystroglycan and integrin are both transmembrane receptors that connect the cytoskeleton inside muscle cells to the extracellular matrix outside muscle cells, maintaining proper adhesion and function of muscle. The position and abundance of Dystroglycan relative to integrins is thought to be important for muscle adhesion and function. The subcellular localization and quantification of these receptor proteins can be determined at the nanometer scale by FPALM super-resolution microscopy. We used FPALM to determine localizations of Dystroglycan and integrin proteins in muscle fibers of intact zebrafish (

Indexed as

Danio rerioDystroglycanfluorescenceFPALMintegrinslocalization microscopymuscle fibersmuscular dystrophysuper-resolutionzebrafish

Identifiers

PMID37509580
PMCPMC10377463
OpenAlexW4383736817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.