Evidence map›Paper›PMID 37509559›Full record

ReviewBiomedicines2023

A Dusty Road for Astronauts.

Silvana Miranda, Shannon Marchal, Lina Cumps, Jenne Dierckx, Marcus Krüger, Daniela Grimm, Sarah Baatout, Kevin Tabury, Bjorn Baselet

Abstract readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [Mechanisms and protective strategies for astronaut skin injury in deep space environments].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. [Effects of lunar soil simulant and Earth soil on lung injury in mice].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  7. Martian samples, hazards, and biosecurity: Between science and bioethics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Silvana MirandaRadiobiology Unit, Belgian Nuclear Research Centre SCK CEN, 2400 Mol, Belgium.ORCID 0000-0003-1365-1657
Shannon MarchalDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.ORCID 0000-0002-5987-2159
Lina CumpsRadiobiology Unit, Belgian Nuclear Research Centre SCK CEN, 2400 Mol, Belgium.
Jenne DierckxRadiobiology Unit, Belgian Nuclear Research Centre SCK CEN, 2400 Mol, Belgium.
Marcus KrügerDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.ORCID 0000-0003-1120-0246
Daniela GrimmDepartment of Microgravity and Translational Regenerative Medicine, Otto von Guericke University, 39106 Magdeburg, Germany.ORCID 0000-0002-4991-3105
Sarah BaatoutRadiobiology Unit, Belgian Nuclear Research Centre SCK CEN, 2400 Mol, Belgium.ORCID 0000-0001-8110-751X
Kevin TaburyRadiobiology Unit, Belgian Nuclear Research Centre SCK CEN, 2400 Mol, Belgium.ORCID 0000-0002-8004-3718
Bjorn BaseletRadiobiology Unit, Belgian Nuclear Research Centre SCK CEN, 2400 Mol, Belgium.

Funding

Belgian Federal Science Policy Office PEA_4000140806European Space Agency PEA_4000140806German Aerospace Center 50WB2219
6 · The paper itself

Abstract

The lunar dust problem was first formulated in 1969 with NASA's first successful mission to land a human being on the surface of the Moon. Subsequent Apollo missions failed to keep the dust at bay, so exposure to the dust was unavoidable. In 1972, Harrison Schmitt suffered a brief sneezing attack, red eyes, an itchy throat, and congested sinuses in response to lunar dust. Some additional Apollo astronauts also reported allergy-like symptoms after tracking dust into the lunar module. Immediately following the Apollo missions, research into the toxic effects of lunar dust on the respiratory system gained a lot of interest. Moreover, researchers believed other organ systems might be at risk, including the skin and cornea. Secondary effects could translocate to the cardiovascular system, the immune system, and the brain. With current intentions to return humans to the moon and establish a semi-permanent presence on or near the moon's surface, integrated, end-to-end dust mitigation strategies are needed to enable sustainable lunar presence and architecture. The characteristics and formation of Martian dust are different from lunar dust, but advances in the research of lunar dust toxicity, mitigation, and protection strategies can prove strategic for future operations on Mars.

Indexed as

Apollo programinflammationlunar dustregolithtoxicity

Identifiers

PMID37509559
PMCPMC10377461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.