Evidence map›Paper›PMID 37509458›Full record

ArticleBiomedicines2023

Immunohistochemical Analysis of Single-Stranded DNA Binding Protein 2 in Non-Melanoma Skin Cancers.

Seongsik Bang, Hwangkyu Son, Hyebin Cha, Kihyuk Song, Hosub Park, Hyunsung Kim, Joo Yeon Ko, Jaekyung Myung, Seungsam Paik

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Seongsik BangDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.ORCID 0000-0002-6872-5986
Hwangkyu SonDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.
Hyebin ChaDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.
Kihyuk SongDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.
Hosub ParkDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.
Hyunsung KimDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.ORCID 0000-0002-8935-7414
Joo Yeon KoDepartment of Dermatology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.
Jaekyung MyungDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.ORCID 0000-0001-9612-5323
Seungsam PaikDepartment of Pathology, Seoul Hospital, Hanyang University College of Medicine, Seoul 04763, Republic of Korea.
Hanyang University Seoul Hospital · KR

Funding

Hanyang University HY-202200000003472
6 · The paper itself

Abstract

Single-stranded DNA binding protein 2 (SSBP2) is a tumor suppressor candidate. In this study, the expression level and clinicopathological significance of SSBP2 in squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) were evaluated. We also identified biological pathways associated with a set of genes potentially related to SSBP2. Immunohistochemistry (IHC) was performed on 70 SCC and 146 BCC cases to assess SSBP2 expression semi-quantitatively. In addition, the associations between SSBP2 expression and clinicopathological characteristics were analyzed. Gene ontology (GO) enrichment analysis was performed using publicly available data and web-based bioinformatics tools. Compared with BCC, SCC had a significantly low SSBP2 expression (

Indexed as

basal cell carcinomaimmunohistochemistrynon-melanoma skin cancersingle-stranded DNA binding protein 2squamous cell carcinomaSSBP2

Identifiers

PMID37509458
PMCPMC10376428
OpenAlexW4382060915

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.