Evidence map›Paper›PMID 37509342›Full record

ArticleCancers2023

DICER1 Syndrome: A Multicenter Surgical Experience and Systematic Review.

Claudio Spinelli, Marco Ghionzoli, Linda Idrissi Sahli, Carla Guglielmo, Silvia Frascella, Silvia Romano, Carlo Ferrari, Fabrizio Gennari, Giovanni Conzo, Riccardo Morganti and 11 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Cancers · 2025
    Review
  4. Article
  5. Review
  6. The Histological Spectrum of DICER1-Associated Neoplasms.Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 1 country.

Claudio SpinelliDivision of Pediatric Surgery, Department of Surgical Pathology, University of Pisa, 56126 Pisa, Italy.
Marco GhionzoliDivision of Pediatric Surgery, Department of Surgical Pathology, University of Pisa, 56126 Pisa, Italy.
Linda Idrissi SahliDivision of Pediatric Surgery, Department of Surgical Pathology, University of Pisa, 56126 Pisa, Italy.ORCID 0009-0007-5281-6254
Carla GuglielmoDivision of Pediatric Surgery, Department of Surgical Pathology, University of Pisa, 56126 Pisa, Italy.
Silvia FrascellaDivision of Pediatric Surgery, Department of Surgical Pathology, University of Pisa, 56126 Pisa, Italy.
Silvia RomanoDepartmental Section of Medical Genetics, S. Chiara Hospital, 56126 Pisa, Italy.
Carlo FerrariDivision of Pediatric Surgery, Regina Margherita Hospital, 10126 Turin, Italy.
Fabrizio GennariDivision of Pediatric Surgery, Regina Margherita Hospital, 10126 Turin, Italy.
Giovanni ConzoDivision of General and Oncologic Surgery-Department of Cardiothoracic Sciences, University of Campania "Luigi Vanvitelli", Via Pansini 1, 80131 Naples, Italy.
Riccardo MorgantiSection of Statistics, University Hospital of Pisa, 56124 Pisa, Italy.ORCID 0000-0001-7783-0262
Luigi De NapoliDivision of Endocrine Surgery, Department of Surgical, Medical, Molecular Pathology and of the Critic Area, University of Pisa, 56126 Pisa, Italy.
Lucia QuagliettaNeuro-Oncology Unit, Department of Paediatric Oncology, Santobono-Pausilipon Children's Hospital, 80123 Naples, Italy.
Lucia De MartinoNeuro-Oncology Unit, Department of Paediatric Oncology, Santobono-Pausilipon Children's Hospital, 80123 Naples, Italy.
Stefania PicarielloNeuro-Oncology Unit, Department of Paediatric Oncology, Santobono-Pausilipon Children's Hospital, 80123 Naples, Italy.
Anna GrandoneDepartment of Woman, Child of General and Specialized Surgery, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
Caterina LuongoDepartment of Woman, Child of General and Specialized Surgery, University of Campania "L. Vanvitelli", 80138 Naples, Italy.
Antonella GambaleCEINGE Advanced Biotechnology, 80131 Naples, Italy.
Armando PatrizioDepartment of Emergency Medicine, Azienda Ospedaliero-Universitaria Pisana, 56126 Pisa, Italy.ORCID 0000-0003-1090-4794
Poupak FallahiDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Alessandro AntonelliDepartment of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-5211-6342
Silvia Martina FerrariDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
University of Pisa · ITSantobono Children's Hospital · ITUniversity of Campania "Luigi Vanvitelli" · ITOspedale Regina Margherita · ITAzienda Ospedaliera Universitaria Pisana · ITFederico II University Hospital · ITOspedale Santa Chiara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DICER1 syndrome is a rare genetic disorder that predisposes patients to the development of malignant and non-malignant diseases. Presently, DICER1 syndrome diagnosis still occurs late, usually following surgical operations, affecting patients' outcomes, especially for further neoplasms, which are entailed in this syndrome. For this reason, herein we present a multicenter report of DICER1 syndrome, with the prospective aim of enhancing post-surgical surveillance. A cohort of seven patients was collected among the surgical registries of Pediatric Surgery at the University of Pisa with the General and Oncologic Surgery of Federico II, University of Naples, and the Pediatric Surgery, Regina Margherita Hospital, University of Turin. In each case, the following data were analyzed: sex, age at diagnosis, age at first surgery, clinical features, familial, genetic investigations, and follow-up. A comprehensive literature review of DICER1 cases, including case reports and multicenter studies published from 1996 to June 2022, was performed. Eventually, the retrieved data from the literature were compared with the data emerging from our cohort of patients.

Indexed as

childrenDICER1genetic mutationneoplasmssurgery

Identifiers

PMID37509342
PMCPMC10377723
OpenAlexW4384821528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.