Evidence map›Paper›PMID 37509253›Full record

ArticleCancers2023

How Asian Breast Cancer Patients Experience Unequal Incidence of Chemotherapy Side Effects: A Look at Ethnic Disparities in Febrile Neutropenia Rates.

Zi Lin Lim, Peh Joo Ho, Mikael Hartman, Ern Yu Tan, Nur Khaliesah Binte Mohamed Riza, Elaine Hsuen Lim, Phyu Nitar, Joint Breast Cancer Registry Jbcr, Fuh Yong Wong, Jingmei Li

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Zi Lin LimGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore.ORCID 0000-0001-7854-8728
Peh Joo HoGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore.ORCID 0000-0002-3017-4023
Mikael HartmanSaw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore.ORCID 0000-0001-5726-9965
Ern Yu TanDepartment of General Surgery, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Nur Khaliesah Binte Mohamed RizaSaw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore.
Elaine Hsuen LimDivision of Medical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.
Phyu NitarDepartment of Cancer Informatics, National Cancer Centre Singapore, Singapore 169610, Singapore.
Joint Breast Cancer Registry JbcrDivision of Radiation Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.
Fuh Yong WongDivision of Radiation Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.
Jingmei LiGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Singapore.ORCID 0000-0001-8587-7511
Agency for Science, Technology and Research · SGNational Cancer Centre Singapore · SGNational University of Singapore · SGNanyang Technological University · SG

Funding

Agency for Science, Technology and Research NANational Medical Research Council NMRC/CSA-SI/0015/2017National University Cancer Institute NMRC/CG/NCIS/2010, NMRC/CG/012/2013, CGAug16M005National University of Singapore NUS Start-Up GrantSaw Swee Hock School of Public Health SSHSPH-Res-Prog-BCPPYong Loo Lin School of Medicine NUHSRO/2020/121/BCSPP/LOA, Asian Breast Cancer research Fund
6 · The paper itself

Abstract

The majority of published findings on chemotherapy-induced febrile neutropenia (FN) are restricted to three ethnic groups: Asians, Caucasians, and African Americans. In this two-part study, we examined FN incidence and risk factors in Chinese, Malay, and Indian chemotherapy-treated breast cancer (BC) patients. Hospital records or ICD codes were used to identify patients with FN. In both the Singapore Breast Cancer Cohort (SGBCC) and the Joint Breast Cancer Registry (JBCR), the time of the first FN from the start of chemotherapy was estimated using Cox regression. Multinomial regression was used to evaluate differences in various characteristics across ethnicities. FN was observed in 170 of 1014 patients in SGBCC. The Cox model showed that non-Chinese were at higher risk of developing FN (HR

Indexed as

breast cancerchemotherapyepidemiologyethnicityfebrile neutropenia

Identifiers

PMID37509253
PMCPMC10377556
OpenAlexW4384131175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.