Evidence map›Paper›PMID 37509182›Full record

ArticleBiomolecules2023

Yeast Models of Amyotrophic Lateral Sclerosis Type 8 Mimic Phenotypes Seen in Mammalian Cells Expressing Mutant VAPB

AnnaMari L Stump, Daniel J Rioux, Richard Albright, Guiliano L Melki, Derek C Prosser

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

AnnaMari L StumpDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23284, USA.
Daniel J RiouxDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23284, USA.
Richard AlbrightDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23284, USA.
Guiliano L MelkiDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23284, USA.
Derek C ProsserDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23284, USA.ORCID 0000-0002-6738-2758
Virginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that results in the loss of motor neurons and can occur sporadically or due to genetic mutations. Among the 30 genes linked to familial ALS, a P56S mutation in

Indexed as

Amyotrophic Lateral SclerosisNeurodegenerative DiseasesAnimalsHumansMammalsMutationSaccharomyces cerevisiaeVesicular Transport ProteinsVAPB protein, humanVesicular Transport ProteinsALSALS8amyotrophic lateral sclerosisendoplasmic reticulummembrane contact siteneurodegenerationSaccharomyces cerevisiaeVAPByeast

Identifiers

PMID37509182
PMCPMC10377116
OpenAlexW4384931967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.