Evidence map›Paper›PMID 37509180›Full record

ReviewBiomolecules2023

Essential Oils: Chemistry and Pharmacological Activities.

Damião P de Sousa, Renan Oliveira S Damasceno, Riccardo Amorati, Hatem A Elshabrawy, Ricardo D de Castro, Daniel P Bezerra, Vitória Regina V Nunes, Rebeca C Gomes, Tamires C Lima

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
178citing papers in PubMed, 4 pooled it
64.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

178 citing papers in PubMed, 4 syntheses or guidelines pooled it, 318 citations in OpenAlex.

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  14. Molecules (Basel, Switzerland) · 2026
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  19. Intranasal essential oils in therapy: advances in clinical applications and delivery mechanisms.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Review
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118 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Damião P de SousaDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-900, Brazil.ORCID 0000-0002-7180-4896
Renan Oliveira S DamascenoDepartment of Physiology and Pharmacology, Center of Biosciences, Federal University of Pernambuco, Recife 50670-901, Brazil.
Riccardo AmoratiDepartment of Chemistry "G. Ciamician", University of Bologna, Via Gobetti 83, 40129 Bologna, Italy.ORCID 0000-0002-6417-9957
Hatem A ElshabrawyDepartment of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA.ORCID 0000-0002-7771-113X
Ricardo D de CastroDepartment of Clinical and Social Dentistry, Federal University of Paraíba, João Pessoa 58051-970, Brazil.ORCID 0000-0001-7986-7376
Daniel P BezerraInstituto Gonçalo Moniz, Fundação Oswaldo Cruz (IGM-FIOCRUZ/BA), Salvador 40296-710, Brazil.ORCID 0000-0002-6774-2063
Vitória Regina V NunesDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-900, Brazil.
Rebeca C GomesDepartment of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-900, Brazil.
Tamires C LimaDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, Brazil.
Universidade Federal da Paraíba · BRFundação Oswaldo Cruz · BRSam Houston State University · USUniversidade Federal de Pernambuco · BRUniversidade Federal de Sergipe · BRUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is presented to better understand the relationship of chemical aspects with the bioactivity of these products. Next, the antioxidant, anti-inflammatory, antitumor, and antimicrobial activities are discussed. The mechanisms of action against various types of viruses are also addressed. The data show that the multiplicity of pharmacological properties of essential oils occurs due to the chemical diversity in their composition and their ability to interfere with biological processes at cellular and multicellular levels via interaction with various biological targets. Therefore, these natural products can be a promising source for the development of new drugs.

Indexed as

Oils, VolatileVirusesAnti-Inflammatory AgentsAntioxidantsPlant OilsAnti-Inflammatory AgentsAntioxidantsOils, VolatilePlant Oilsantibacterialanticancerantifungalanti-inflammatoryantioxidantantiviralmedicinal plantsmetabolitesnatural productsvolatiles

Identifiers

PMID37509180
PMCPMC10377445
OpenAlexW4384826655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.