Evidence map›Paper›PMID 37509170›Full record

ArticleBiomolecules2023

Preclinical Characterization of a Stabilized Gastrin-Releasing Peptide Receptor Antagonist for Targeted Cancer Theranostics.

Ayman Abouzayed, Panagiotis Kanellopoulos, Alisa Gorislav, Vladimir Tolmachev, Theodosia Maina, Berthold A Nock, Anna Orlova

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. RM2 and DB15 analogues bearing [EJNMMI radiopharmacy and chemistry · 2025
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  5. Two Novel [ACS omega · 2024
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  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ayman AbouzayedDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Panagiotis KanellopoulosDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Alisa GorislavDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Vladimir TolmachevDepartment of Immunology, Genetics and Pathology, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0002-6122-1734
Theodosia MainaMolecular Radiopharmacy, INRaSTES, NCSR "Demokritos", 15310 Athens, Greece.ORCID 0000-0002-1123-2486
Berthold A NockMolecular Radiopharmacy, INRaSTES, NCSR "Demokritos", 15310 Athens, Greece.ORCID 0000-0002-6028-9112
Anna OrlovaDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0001-6120-2683
Uppsala University · SENational Centre of Scientific Research "Demokritos" · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiolabeled gastrin-releasing peptide receptor (GRPR) antagonists have shown great promise for the theranostics of prostate cancer; however, their suboptimal metabolic stability leaves room for improvements. It was recently shown that the replacement of Gly

Indexed as

Prostatic NeoplasmsReceptors, BombesinAnimalsCell Line, TumorHumansMaleMicePrecision MedicineReceptors, BombesinGRPR antagonistneprilysinPC-3 cellsprostate cancertheranostics

Identifiers

PMID37509170
PMCPMC10377574
OpenAlexW4384558035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.